Krebs (citric acid) cycle and oxidative phosphorylation Flashcards
How many molecules of acetyl CoA are produced from a single molecule of glucose for participation in the Krebs cycle?
2
How are electrons extracted from the citric acid cycle for use in the electron transport chain?
Reduction of NAD+ and FAD
A molecule is said to be reduced when it
Undergoes the addition of electrons or decrease in oxidation state
The citric acid cycle produces
FADH2 and NADH
Large concentrations of what would inhibit the entry of pyruvate into the citric acid cycle?
NADH
What are essential reactants for the formation of acetyl CoA?
Coenzyme A and pyruvate
What are products of the conversion of pyruvate into acetyl CoA?
- ATP
- NADH
- Acetyl CoA
ATP synthase is located in
Inner mitochondrial membrane
How many ATP are produced per molecule of NADH?
3
How many ATP are produced per molecule of FADH2?
2
The major product of the electron transport chain and oxidative phosphorylation is
ATP
What increase the activity of the electron transport chain and oxidative phosphorylation?
High [ADP]
The pH of the cytosol ranges around
7
Reactive oxygen species are common causes of
- Apoptosis
- Cellular damage
Superoxide dismutase is an enzyme which functions to
Neutralize oxygen radicals