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Step 1 > Pharm 16 > Flashcards

Pharm 16 Flashcards

2
Q

Cholinomimetics that increase outflow, open trabecular meshwork, and cause ciliary muscle contraction

A

Pilocarpine, carbachol, physostigmine

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3
Q

Nonselective alpha agonists that increases outflow, probably via the uveoscleral veins

A

Epinephrine, dipivefrin

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4
Q

Selective alpha agonists that decreases aqueous secretion

A

Apraclonidine, brimonidine

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5
Q

This diuretic decreases aqueous secretion due to lack of HCO3- ion. Causes drowsiness and paresthesias, alkalinization of the urine may precipitate calcium salts, hypokalemia, acidosis

A

Acetazolamide

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6
Q

This agent cause increased aqueous outflow

A

Prostaglandin PGF2a

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7
Q

Block L-type calcium channel

A

Calcium channel blockers

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8
Q

CCB with predominate effect on arteriole dilation

A

Nifedipine

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9
Q

Beta-blockers should be used cautiously in

A

Asthma (bronchospastic effects), diabetes (block signs of hypoglycemia) and peripheral vascular disease

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10
Q

Non-selective Beta-blocker also used for migraine prophylaxis

A

Propranolol

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11
Q

Non-selective Alpha1blockers use to treat pheochromocytoma

A

Phenoxybenzamine

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12
Q

For rebound HTN from rapid clonidine withdrawal

A

Phentolamine

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13
Q

Presynaptic Alpha 2 agonist used in HTN

A

Clonidine, and methyldopa

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14
Q

SE of methyldopa

A

Positive Comb’s test, depression

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15
Q

SE of clonidine

A

Rebound HTN, sedation, dry mouth

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16
Q

Ganglionic blockers formerly used in HTN

A

Trimethaphan, and hexamethonium

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17
Q

Direct vasodilator of arteriolar smooth muscle

A

Hydralazine

18
Q

Arterial vasodilator that works by opening K+ channels

A

Minoxidil

19
Q

SE of minoxidil

A

Hypertrichosis

20
Q

IV Drug used Hypertensive Crisis

A

Nitroprusside

21
Q

Nitroprusside vasodilates

A

Arteries and veins

22
Q

Toxicity caused by nitroprusside and treatment

A

Cyanide toxicity treated with sodium thiosulfate

23
Q

Carbonic anhydrase inhibitor

A

Acetazolamide

24
Q

MOA of loop diuretics

A

inhibits Na+/K+/2Cl- cotransport

25
Q

Aminoglycosides used with loop diuretics potentiate adverse effect

A

Ototoxicity

26
Q

MOA of thiazide diuretics

A

Inhibit Na+/Cl- cotransport

27
Q

Class of drugs that may cause cross-sensitivity with thiazide diuretics

A

Sulfonamides

28
Q

Used for SIADH

A

Demeclocycline

29
Q

SE of demeclocycline

A

Bone marrow and teeth discoloration for children under 8 years of age

30
Q

Other side effects of Quinidine

A

Thrombocytopenic purpura, and CINCHONISM

31
Q

Major drug interaction with Quinidine

A

Increases concentration of Digoxin

32
Q

DOC for digoxin induced arrhythmias

A

Phenytoin

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