MSK Flashcards
1 cause of Osteomyelitis
SA
Osteomyelitis in diabetics & foot puncture wound
PA
Osteomyelitis in hip replacement
Staph epi
Anti-cyclic citrullinated peptide (CCO)
RA
- HLA-DR4
Tumor or cystic clearing “soap bubble” lesion in epiphysis of metacarpal bones, contains giant cells
Giant cell tumor of bone
Teenager with raised periosteum in the metaphysis of the femur
Osteosarcoma
- “Codman’s triangle & sunburst pattern”
Well demarcated lytic lesion with sclerosis <2cm in the femur
Osteoid osteoma
Well demarcated lytic lesion with sclerosis >2cm in the femur
Osteoblastoma
Teenager with onion skin or sunburst pattern in diaphysis of femur, (11;22)
Ewing sarcoma
Unable to relax hand grip, muscle weakness, atrophy, cataracts, testicular failure, balding, spike on EMG
Myotonic dystrophy
- CTG expansion of DMPK
Often co-exists w/ temporal arteritis
Polymyalgia rheumatica
- shoulder and pelvic girdle sitffness
Painless loss of vision in 1 eye - curtain
Retinal artery - red macula
Ophthalmic artery
Temporal arteritis
Central scotoma
Blow to back of head
Pre-eclampsia
Macular degeneration
Mosaic bone pattern, inc alk phos, hearing loss
Paget disease
- inc cell turnover
- HIGH OUTPUT HF
Type I collagen deficiency
Osteogenesis imperfecta
Young girl with precocious puberty, short stature, cafe au lait spots and irregular pigmented patches of skin
McCune-Albright syndrome
Kid w/ small round blue cells, stain + for myoglobin, actin, demin
Rhabdomyosarcoma
Bone pain relieved by aspirin
Osteoid osteoma
Only epiphyseal tumor
Giant cell
Tumor of small bones of hand (metacarpals) and feet
Chondroma
UE weakness, can’t comb hair, rash on eyelids, red papules on elbows, knees, knuckles
Dermatomyostitis
