HY Pharm 6 Flashcards

2
Q

These agents decrease blood flow or increase blood pressure, are local decongestant, and used in therapy of spinal shock (temporary maintenance of blood pressure which may help maintain perfusion)

A

*Alpha1 agonists

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3
Q

Alpha 1 agonist toxicity

A

*Hypertension

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4
Q

Selective Alpha 1 blocker used for hypertension, BPH, may cause first dose orthostatic hypotension, reflex tachycardia

A

*Prazosin, terazosin, doxazosin

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5
Q

Selective B1 Blockers that may be useful in treating cardiac conditions in patients with asthma

A

*Acebutolol, atenolol, esmolol, metoprolol

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6
Q

This beta blocker lacks local anesthetic activity (decreases protective reflexes and increases the risk of corneal ulceration) and used in treating glaucoma

A

*Timolol

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7
Q

These Beta blockers decrease aqueous secretion

A

*Timolol (nonselective), betaxolol (B1 selective)

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8
Q

Inhibit angiotensin-converting enzyme (ACE)

A

*ACE inhibitors

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9
Q

Captopril and enalapril (-OPRIL ending) are

A

*ACE inhibitors

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10
Q

SE of ACE inhibitors

A

*Dry cough, hyperkalemia

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11
Q

ACE inhibitors are contraindicated in

A

*Pregnancy & Hyperkalemia

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12
Q

Losartan and valsartan block

A

*Angiotensin receptor blockers (ARB)

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13
Q

Angiotensin receptor blockers do NOT cause

A

*Dry cough

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14
Q

SE of CCB

A

*Constipation, edema, AV block, cardiac depression and headache

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15
Q

Reduce heart rate, contractility, and O2 demand

A

*Beta-blockers

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16
Q

Cardioselective Beta 1-blockers

A

*Atenolol, acebutolol, betaxolol, esmolol and metoprolol (A BEAM)

(Good for co-morbidities like asthma)

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17
Q

SE of beta blockers

A

*Bradycardia, SEXUAL DYSFUNCTION, decrease in HDL, and increase in Triglycerols (TG)

18
Q

Alpha 1 selective blockers

A

*Prazosin, terazosin and doxazosin (-AZOSIN ending)

19
Q

A1a-selective blocker used for BPH

A

*Tamsulosin (Flomax)

20
Q

SE of alpha blockers

A

*Orthostatic hypotension (especially with first dose) and reflex tachycardia

21
Q

Methyldopa is contraindicated in

A

*Geriatrics due to its CNS (depression) effects

22
Q

SE of hydralazine

A

*Lupus-like syndrome

23
Q

Diuretic used for mountain sickness and glaucoma

A

*Acetazolamide

24
Q

SE of acetazolamide

A

*Paresthesias
Alkalization of the urine (–> Ca stones)
Hypokalemia?
ACIDOSIS
Sulfa allergy
Encephalopathy in patients with hepatic impairment

25
Q

Site of action of loop diuretics

A

*Thick ascending limb

26
Q

SE of loop (furosemide) diuretics

A
*Ototoxicity
HypoK, hypoCa
Dehydration
Allergy (sulfa)
Nephritis
GOUT
(OH DANG)