HY Pharm 6 Flashcards
These agents decrease blood flow or increase blood pressure, are local decongestant, and used in therapy of spinal shock (temporary maintenance of blood pressure which may help maintain perfusion)
*Alpha1 agonists
Alpha 1 agonist toxicity
*Hypertension
Selective Alpha 1 blocker used for hypertension, BPH, may cause first dose orthostatic hypotension, reflex tachycardia
*Prazosin, terazosin, doxazosin
Selective B1 Blockers that may be useful in treating cardiac conditions in patients with asthma
*Acebutolol, atenolol, esmolol, metoprolol
This beta blocker lacks local anesthetic activity (decreases protective reflexes and increases the risk of corneal ulceration) and used in treating glaucoma
*Timolol
These Beta blockers decrease aqueous secretion
*Timolol (nonselective), betaxolol (B1 selective)
Inhibit angiotensin-converting enzyme (ACE)
*ACE inhibitors
Captopril and enalapril (-OPRIL ending) are
*ACE inhibitors
SE of ACE inhibitors
*Dry cough, hyperkalemia
ACE inhibitors are contraindicated in
*Pregnancy & Hyperkalemia
Losartan and valsartan block
*Angiotensin receptor blockers (ARB)
Angiotensin receptor blockers do NOT cause
*Dry cough
SE of CCB
*Constipation, edema, AV block, cardiac depression and headache
Reduce heart rate, contractility, and O2 demand
*Beta-blockers
Cardioselective Beta 1-blockers
*Atenolol, acebutolol, betaxolol, esmolol and metoprolol (A BEAM)
(Good for co-morbidities like asthma)