Pharm 15

Question 2

Limiting adverse effect of ganglion blockade that patients usually are unable to tolerate

Answer 2

Severe hypertension

Question 3

Reversal of blockade by neuromuscular blockers

Answer 3

Cholinesterase inhibitors

Question 4

Tubocurarine is the prototype, pancuronium, atracurium, vecuronium are newer short acting agent, produce competitive block at end plate nicotinic receptor, causing flaccid paralysis

Answer 4

Nondepolarizing Neuromuscular Blockers

Question 5

Only member of depolarizing neuromuscular blocker, causes fasciculation during induction and muscle pain after use

Answer 5

Succinylcholine

Question 6

Chemical antagonists that bind to the inhibitor of ACh Estrace and displace the enzyme (if aging has not occurred)

Answer 6

Cholinesterase Regenerators

Question 7

Used to treat patients exposed to insecticides such as parathion

Answer 7

Pralidoxime

Question 8

Phenylisopropylamines that are used legitimately and abused for narcolepsy, attention deficit disorder, and weight reduction

Answer 8

Amphetamines

Question 9

Alpha agonist used to produce mydriasis and reduce conjunctival itching and congestion caused by irritation or allergy, it does not cause cycloplegia

Answer 9

Phenylephrine

Question 10

Epinephrine and dipivefrin are used for

Answer 10

Glaucoma

Question 11

Newer alpha 2 agonist (apraclonidine and brimonidine) treat glaucoma

Answer 11

Reduce aqueous synthesis

Question 12

Short acting Beta 2 agonists that is drug of choice in treatment of acute asthma but not recommended for prophylaxis

Answer 12

Albuterol

Question 13

Longer acting Beta 2 agonists is recommended for prophylaxis of asthma

Answer 13

Salmeterol

Question 14

These agents increase blood flow and may be beneficial in treatment of acute heart failure and some types of shock

Answer 14

Beta1 agonists

Question 15

Shock due to septicemia or myocardial infarction is made worse by

Answer 15

Increasing afterload and tissue perfusion declines

Question 16

Often mixed with local anesthetic to

Answer 16

Reduce the loss from area of injection

Question 17

Chronic orthostatic hypotension can be treated with

Answer 17

Midodrine

Question 18

Beta 2 agonist used to suppress premature labor, but cardiac stimulatory effects may be hazardous to mother and fetus

Answer 18

Terbutaline

Question 19

Long acting sympathomimetic, sometimes used to improve urinary continence in children and elderly with enuresis

Answer 19

Ephedrine

Question 20

Beta 1 agonist toxicity

Answer 20

Sinus tachycardia and serious arrhythmias

Question 21

Beta 2 agonist toxicity

Answer 21

Skeletal muscle tremor

Question 22

The selective agents loose their selectivity at

Answer 22

high doses

Question 23

Nonselective alpha-blocking drug, long acting and irreversible, and used to treat pheochromocytoma. Blocks 5-HT, so occasionaly used for carcinoid tumor. Blocks H1 and used in mastocytosis

Answer 23

Phenoxybenzamine

Question 24

Nonselective alpha-blocking drug, short acting and reversible, used for rebound HTN from rapid clonidine withdrawal, and Raynaud’s phenomena

Answer 24

Phentolamine

Question 25

Selective Alpha 2 blocker used for impotence (controversial effectiveness)

Answer 25

Yohimbine

Question 26

Combined alpha and beta blocking agents that may have application in treatment of CHF

Answer 26

Labetalol and carvedilol

Question 27

Beta blockers partial agonist activity (intrinsic sympathomimetic activity) cause some bronchodilation and may have an advantage in treating patients with asthma

Answer 27

Pindolol and acebutolol

Question 28

This parenteral beta blocker is a short acting

Answer 28

Esmolol

Question 29

This beta blocker is the longest acting

Answer 29

Nadolol

Question 30

These beta blockers are less lipid soluble

Answer 30

Acebutolol and atenolol

Question 31

This beta blocker is highly lipid soluble and may account for side effects such as nightmares

Answer 31

Propranolol

Question 32

Clinical uses of these agents include treatment of HTN, angina, arrhythmias, and chronic CHF

Answer 32

Beta blockers

Question 33

Toxicity of these agents include bradycardia, AV blockade, exacerbation of acute CHF, signs of hypoglycemia may be masked (tachycardia, tremor, and anxiety)

Answer 33

Beta blockers