Pharm 10

Question 2

DOCs for status epilepticus

Answer 2

IV diazepam (or lorazapam) followed by phenytoin

Question 3

Drugs that can be used for infantile spasms

Answer 3

Corticosteroids

Question 4

Anti-seizure drugs used also for bipolar affective disorder (BAD)

Answer 4

Valproic acid, carbamazepine, phenytoin and gabapentin

Question 5

Anti-seizure drugs used also for Trigeminal neuralgia

Answer 5

Carbamazepine

Question 6

Anti-seizure agent that exhibits non-linear metabolism, highly protein bound, causes fetal hydantoin syndrome, and stimulates hepatic metabolism

Answer 6

Phenytoin

Question 7

Anti-seizure agent that induces formation of liver drug-metabolism enzymes, is teratogen and can cause craniofacial anomalies and spina bifida

Answer 7

Carbamazepine

Question 8

Agent that inhibits hepatic metabolism, is hepatotoxic and teratogen that can cause neural tube defects and gastrointestinal distress

Answer 8

Valproic acid

Question 9

Laboratory value required to be monitored for patients on valproic acid

Answer 9

Serum ammonia and LFT’s

Question 10

SE for Lamotrigine

Answer 10

Stevens-Johnson syndrome

Question 11

SE for Felbamate

Answer 11

Aplastic anemia and acute hepatic failure

Question 12

Anti-seizure medication also used in the prevention of migraines

Answer 12

Valproic acid

Question 13

Carbamazepine may cause

Answer 13

Agranulocytosis

Question 14

Anti-seizure drugs used as alternative drugs for mood stabilization

Answer 14

Carbamazepine, gabapentin, lamotrigine, and valproic acid

Question 15

MOA of general anesthetics

Answer 15

Unclear, thought to increase the threshold for firing of CNS neurons

Question 16

Inhaled anesthetic with a low blood/gas partition coefficient

Answer 16

Nitrous oxide

Question 17

Inversely related to potency of anesthetics

Answer 17

Minimum alveolar anesthetic concentration (MAC)

Question 18

Inhaled anesthetics metabolized by liver enzymes which has a major role in the toxicity of these agents

Answer 18

Halothane and methoxyflurane

Question 19

Most inhaled anesthetics SE

Answer 19

Decrease arterial blood pressure

Question 20

Inhaled anesthetics are myocardial depressants

Answer 20

Enflurane and halothane

Question 21

Inhaled anesthetic causes peripheral vasodilation

Answer 21

Isoflurane

Question 22

Inhaled anesthetic that may sensitize the myocardium to arrhythmogenic effects of catecholamines and has produced hepatitis

Answer 22

Halothane

Question 23

Inhaled anesthetics, less likely to lower blood pressure than other agents, and has the smallest effect on respiration

Answer 23

Nitrous oxide

Question 24

Fluoride released by metabolism of this inhaled anesthetic may cause renal insufficiency

Answer 24

Methoxyflurane

Question 25

Prolonged exposure to this inhaled anesthetic may lead to megaloblastic anemia

Answer 25

Nitrous oxide

Question 26

Pungent inhaled anesthetic which leads to high incidence of coughing and vasospasm

Answer 26

Desflurane

Question 27

IV barbiturate used as a pre-op anesthetic

Answer 27

Thiopental

Question 28

Benzodiazepine used adjunctively in anesthesia

Answer 28

Midazolam

Question 29

This produces “dissociative anesthesia”, is a cardiovascular stimulant which may increases intracranial pressure, and hallucinations occur during recovery

Answer 29

Ketamine

Question 30

State of analgesia and amnesia produced when fentanyl is used with droperidol and nitrous oxide

Answer 30

Neuroleptanesthesia

Question 31

Produces both rapid anesthesia and recovery, has antiemetic activity and commonly used for outpatient surgery, may cause marked hypotension

Answer 31

Propofol

Question 32

Most commonly abused in health care professionals

Answer 32

Heroin, morphine, oxycodone, meperidine and fentanyl

Question 33

This route is associated with rapid tolerance and psychologic dependence

Answer 33

IV administration

Question 34

Lacrimation, rhinorrhea, yawning, sweating, weakness, gooseflesh, nausea, and vomiting, tremor, muscle jerks, and hyperpnea are signs of this syndrome

Answer 34

Abstinence syndrome

Question 35

Treatment for opioid addiction

Answer 35

Methadone, followed by slow dose reduction