HY Pharm 3 Flashcards
Used in pediatrics to maintain patency of ductus arteriosis
*PGE1 (Alprostadil)
Prostaglandin used in the treatment impotence
*PGE1 (Alprostadil)
MOA and effect of nitric oxide
*Stimulates cGMP which leads to vascular smooth muscle relaxation
Muscarinic antagonist used in asthma
*Ipratropium
MOA action of cromolyn
*Mast cell stabilizer
SE of long term (>5 days) corticosteroid therapy and remedy
*Adrenal suppression and weaning slowly, respectively
MOA of quinolones
**Inhibit DNA gyrase
Drug used for MRSA
*Vancomycin
Vancomycin MOA
**Blocks peptidoglycan synthesis
Meningitis prophylaxis in exposed patients
*Rifampin (orange fluids)
Technique used to diagnose perianal itching, and the drug used to treat it
*Scotch tape technique and mebendazole
MOA of sulfonamides
*Inhibit dihydropteroate synthase
Cheap wide spectrum antibiotic DOC of otitis media
**Amoxicillin
DOC for tx of pseudomembranous colitis
**Metronidazole
Anemia caused by trimethoprim
*Megaloblastic anemia
DOC for giardia, bacterial vaginosis, pseudomembranous colitis, entamoebasis and trichomonas
*Metronidazole
Treatment for TB patients (think RIPE)
- Rifampin (orange fluids),
- Isoniazid (peripheral neuropathy)
- Pyrazinamide (gout)
- Ethambutol (color-blindness)
Common side effect of Rifampin
*Orange urine discoloration
DOC for influenza A and B
*1st - Zanamivir
Asthma = Oseltamivir
DOC for RSV
*Ribavirin
Major effect of benzodiazepines on sleep at high doses
*REM is decreased
Reason benzos are used cautiously in pregnancy
*Ability to cross the placenta
Antidote to benzodiazepine overdose (antagonist that reverses the CNS effects)
*Flumazenil
Agent that is metabolized to acetaldehyde by alcohol dehydrogenase and microsomal ethanol-oxidizing system (MEOS)
*Ethanol
System that increases in activity with chronic exposure to alcohol and may contribute to tolerance
*Microsomal ethanol oxidizing system MEOS
