HY Pharm 3

Question 2

Used in pediatrics to maintain patency of ductus arteriosis

Answer 2

*PGE1 (Alprostadil)

Question 3

Prostaglandin used in the treatment impotence

Answer 3

*PGE1 (Alprostadil)

Question 4

MOA and effect of nitric oxide

Answer 4

*Stimulates cGMP which leads to vascular smooth muscle relaxation

Question 5

Muscarinic antagonist used in asthma

Answer 5

*Ipratropium

Question 6

MOA action of cromolyn

Answer 6

*Mast cell stabilizer

Question 7

SE of long term (>5 days) corticosteroid therapy and remedy

Answer 7

*Adrenal suppression and weaning slowly, respectively

Question 8

MOA of quinolones

Answer 8

**Inhibit DNA gyrase

Question 9

Drug used for MRSA

Answer 9

*Vancomycin

Question 10

Vancomycin MOA

Answer 10

**Blocks peptidoglycan synthesis

Question 11

Meningitis prophylaxis in exposed patients

Answer 11

*Rifampin (orange fluids)

Question 12

Technique used to diagnose perianal itching, and the drug used to treat it

Answer 12

*Scotch tape technique and mebendazole

Question 13

MOA of sulfonamides

Answer 13

*Inhibit dihydropteroate synthase

Question 14

Cheap wide spectrum antibiotic DOC of otitis media

Answer 14

**Amoxicillin

Question 15

DOC for tx of pseudomembranous colitis

Answer 15

**Metronidazole

Question 16

Anemia caused by trimethoprim

Answer 16

*Megaloblastic anemia

Question 17

DOC for giardia, bacterial vaginosis, pseudomembranous colitis, entamoebasis and trichomonas

Answer 17

*Metronidazole

Question 18

Treatment for TB patients (think RIPE)

Answer 18

• Rifampin (orange fluids),
• Isoniazid (peripheral neuropathy)
• Pyrazinamide (gout)
• Ethambutol (color-blindness)

Question 19

Common side effect of Rifampin

Answer 19

*Orange urine discoloration

Question 20

DOC for influenza A and B

Answer 20

*1st - Zanamivir

Asthma = Oseltamivir

Question 21

DOC for RSV

Answer 21

*Ribavirin

Question 22

Major effect of benzodiazepines on sleep at high doses

Answer 22

*REM is decreased

Question 23

Reason benzos are used cautiously in pregnancy

Answer 23

*Ability to cross the placenta

Question 24

Antidote to benzodiazepine overdose (antagonist that reverses the CNS effects)

Answer 24

*Flumazenil

Question 25

Agent that is metabolized to acetaldehyde by alcohol dehydrogenase and microsomal ethanol-oxidizing system (MEOS)

Answer 25

*Ethanol

Question 26

System that increases in activity with chronic exposure to alcohol and may contribute to tolerance

Answer 26

*Microsomal ethanol oxidizing system MEOS