Osteoporosis Medications

Question 1

aledronate (fosamax)

Answer 1

Prevents bone resorption

1. Give 30 mins prior to medication, food, or beverage in the morning
2. Administer with 8 oz of water
3. Avoid laying down 30 minutes after administration
4. Available as a once daily or once weekly tab
5. Decreases GI-SE and Increase absorption

Question 2

calcitonin (Miacalcin

Answer 2

Opposes the effects of the parathyroid hormone on bone resorption

1. Administer intranasally 1 spray every day and alternate nares
2. Allergy testing is done prior to initiating therapy
3. Nasal exams for irritation
4. Common SE include nasal dryness and irriation

Question 3

lbandronate (Boniva)

Answer 3

Reduces bone resorption. In post menopausal women, it reduces the rate of bone turnover, resulting in a net gain in bone mass.

• Correct hypocalcemia before administering
• Give on empty stomach
• Instruct patient to swallow medication whole with a full glass of water while sitting or standing in an upright position
• Keep patient sitting up or ambulating for 60 minutes after taking medication
• Administered one dose monthly