Neoplasms #3 (1) Flashcards
Screening methods for reproductive cancer
- pap smear
- pelvic exam
Risk Factors Cervical Cancer
- Low socioeconomic status
- Early sexual activity
- Multiple sex partners
- HPV infection
- Smoking
Clinical manifestations of cervical cancer
usually asymptomatic until later stages
Risk factors endometrial cancer
- Estrogen
- Increasing age
- Nulliparty
- Obesity
- HTN
- DM
- Family History of nonpolyposis colorectal cancer
Clinical manifestations of endometrial cancer
abnormal uterine bleeding
Risk factors of ovarian cancer
- Family history ovarian/breast/colon cancer
- Nulliparty
- Increasing age
- High Fat diet
- Early menarche and late menopause
- HRT
- Infertility drugs
Risk factors to vulvar (external genitalia) cancer
- Immunosuppression
- DM
- HTN
- Chronic vuvlar dystrophies (STDS)
Clinical Manifestations of ovarian cancer
- Persistent bloating
- Pelvic or abdominal pain
- Feeling full quickly
- Frequent or urgent urination
- Loss of appetite
- Post-menopausal bleeding
Clinical manifestations of vulvar (external genitalia)
- Vulvular itching or buring
- Pain
- Bleeding
- Discharge
Basal Cell Carcinoma
- 80% of all skin cancers
- Rarely metastasize
- Non-melanoma
- High cure rate when treated early
Assessment of Basal Cell Carcinoma
- Shiny, translucent or pearly nodule
- Sore that continuously heals and then reopens
- Waxy scar
- Reddish iriitated patches of skin
- Most appear on sun-exposed areas: face, ears, scalp, upper trunk
Squamous Cell Carcinoma
- 16% of all skin cancers
- Potential to metastasize when not treated early
- Smoking contributes to formation
Assessment of Squamous cell carcinoma
- Crusted or scaly area of skin with red of inflamed base
- Scale or horn may cover lesion
- May occur inside of mouth and genitalia
- Often found on sun-exposed areas
Melanoma
- Most prevalent form of cancer in women aged 25-29
- 4% of all skin cancers
- Rapidly spreads to lymph system and internal organs
- Once metastasized, prognosis is poor
Assessment of Melanoma
- Often develops in pre-existing mole or what appears to be a new mole
- Asymmetry
- Border Irregularity
- Color variation within lesion
- Diameter >6mm
- Elevation and evolution (change)
Colon Cancer Risk Factors
- Age
- Familial polyposis
- Colorectal polyps
- Chronic IBD
- Family history colorectal cancer
- History breast cancer
- High fat and/or low fiber diet
Screening methods for Colon Cancer
- Begin at age 50
- Begin at age 45 for african americans or family history of colon cancer
- Fecal occult blood testing (FOBT)
- Flexible sigmoidoscopy every 5 years or colonscopy every 10 years
- 2/3 deaths preventable with screening
Clinical manifestations of Colon Cancer
- Non-specific until advanced disease
- Right Sided Cancer: vague, colicky abdominal pain, weakness, fatigue
- Left Sided Cancer: rectal bleeding, constipation, diarrhea, change in stool caliber
Surgical and Treatment Interventions for Colon Cancer
- Abdominal Perineal Resection
- Lower Anterior Resection
- Hemi-colectomy
- Radiation
- Chemotherapy
- Biotherapy
- Targeted therapy