Neoplasms Lecture #2 Flashcards
Neoplasm
Cell growth that is not needed for normal development or replacement of dead or damaged tissue
What are the two types of neoplasms?
- Benign
- Malignant
List examples of benign neoplasms
- Cysts
- Fibroma
- Leiomyoma
What is cancer?
A group of diseases that have the following common characteristics:
- uncontrolled/unregulated cellular growth
- Invade into surrounding tissue
- Spread/metastasize to distant sites
Pathophysiology of cancer cells
Body cells are exposed to personal and environmental conditions that can alter how the cells grow and function
Proliferation - continue to grow regardless of need
Malignant neoplasms characteristics
- Rarely encapsulated
- Poorly differentiated
- Frequent Metastasis
- Frequent Recurrence
- Marked Vascular
- Infiltrative Growth
- Cells abnormal characteristics
Benign neoplasms characteristics
- Usually encapsulated
- Partially differentiated
- No metastasis
- Rare recurrence
- Slight vascular
- Expansive growth
- Cells fairly normal
Grading
cell differentiation
Compares cancer cells with normal parent cells
Lowest rating = 1 well differentiated or closely resembles normal cells
Highest Rating=4 or 5 Poorly differentiated or barely resembles normal cells
Staging
System for describing the size and extent of spread of malignant tissue; used to plan treatment and predict prognosis
Common types of cancer in whites
- Lung
- Prostate
- Breast
- Colorectal
Common types of cancer in asians
- prostate
- breast
- colorectal
- lung
- stomach
Common types of cancer in african americans
- prostate
- breast
- lung
- colorectal
- uterine
common types of cancer in hispanics
- prostate
- breast
- colorectal
- lung
What are the 3 stages of cancer development?
- Initiation
- Promotion
- Progression
Initiation
First stage in normal cells becoming cancer cells. Substances (carcinogens) change the activity of a cell’s genes so the cell becomes cancerous