Lecture 9 - Integument Physiology II Flashcards
Which layer of skin is the thinnest
epidermis
which layer of skin has a thickness that depends on its location in the body
hypodermis
what is the largest population of cells within the epidermis
keratinocytes
order the layers of the epidermis (outer to inner)
stratum granulosum
stratum basale
stratum corneum
stratum spinosum
stratum basale
stratum spinosum
stratum granulosum
stratum corneum
What is the makeup of the stratum basale
mostly keratinocytes - anchor to the dermis, proliferative
what is the makeup of the stratum spinosum
nucleated daughter cells seemingly connected by intracellular bridges (webs)
keratinocytes of the SS synthesize:
a. lamellar granules
b. free sterols
c. glycoproteins
d. all of the above
d. all of the above
What cell layer becomes thickened during viral disease
stratum granulosum
what is the makeup of the stratum granulosum
shrunken nuclei, “granules” in cytoplasm
What is loricrin
an insoluble product of the SG that binds keratin filaments (think brick in the brick-and-mortar model)
what is the makeup of the stratum corneum
anuclear cells, large population of corneocytes
corneocyte
differentiated cell containing cornified envelope (structural support and defense against environmental agents)
on average, how many days does it take for the epidermis to turn over
20-25 days
Come Get Sun Burnt
Corneum, Granulosum, Spinosum, Basale
adnexa
structures found in the dermis