Lecture 50 - Motor Control 1 & 2 Flashcards

1
Q

what is the hierarchy in motor control

A
  1. cerebral cortex
  2. subcortical nuclei
  3. brainstem nuclei and cerebellum
  4. spinal cord
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2
Q

describe the motor neurons in the spinal cord

A

ventral horn (grey matter)
sensory
cholinergic

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3
Q

summarize the patellar reflex in 5 steps

A
  1. tendon tap
  2. activation of muscle spindles via stretching
  3. action potential generated
  4. synapse in the spinal cord - spindle fibers to motor neurons
  5. motor neuron activation
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4
Q

T/F: most reflexes are monosynaptic

A

FALSE - involve one or more interneurons

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5
Q

The “withdrawal” reflex utilizes what general circuitry

A

flexor and cross-extensor reflex arc

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6
Q

what is the righting reflex

A

animal is flipped onto its back or side, the sensory input from the vestibular system and proprioception triggers motor responses

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7
Q

T/F: the righting reflex is dependent on gravity

A

TRUE

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8
Q

vestibular nuclei are involved in

A

modulation of tone in extensor muscles (upright posture)

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9
Q

red nuclei are involved in

A

unconscious stereotyped movements (gait)

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10
Q

what is in charge if high-order control of gait and control of distal muscles for complex movement

A

red nucleus

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11
Q

damage to the cerebellum results in what

A

ataxia

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12
Q

what is the cerebellum in charge of

A

coordinating motor function and executing rapid movements

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13
Q

T/F: cerebellum receives output from the motor cortex and provides “error” correction signals

A

TRUE

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14
Q

the Purkinje fibers do what

A

inhibits unwanted movement

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15
Q

the basal nuclei includes what structures

A

striatum
globus pallidus external
globus pallidus internal

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16
Q

what does the basal nuclei project to

A

the thalamus and subthalamic nuclei

17
Q

what does the basal nuclei receive input from

A

all cortical areas and the substantial nigra

18
Q

what input is associated with the substantial nigra

19
Q

summarize the direct pathway in 4 steps

A
  1. input from the motor cortex
  2. synapse GPe to GPi (inhibitory to inhibitory
  3. sensory input to the motor thalamus
  4. control unwanted movement
20
Q

is the substantial nigra excitatory of inhibitory in the direct pathway

A

excitatory

21
Q

what is the end goal of the indirect pathway

A

stop movement

22
Q

D1 receptors in the ___ pathway facilitate ____

A

direct; excitation

23
Q

D2 receptors in the ___ pathway facilitate ____

A

indirect; inhibition

24
Q

hypokinesia

A

inability to initiate movement (Parkinson’s)

25
hyperkinesia
excessive motor activity (Huntington's)
26
what are the functions of the motor cortex
1. voluntary control 2. proportionately large area devoted to areas of the body w capacity for controlled movements 3. corticospinal (pyramidal) tracts 4. learned, skilled, fine, voluntary control of muscles