Lecture 33 - Anatomy of the Nervous System Flashcards

1
Q

What are the 3 nervous systems

A
  1. Central nervous system
  2. Peripheral nervous system
  3. Enteric nervous system
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2
Q

The CNS contains the

A

brain
spinal cord

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3
Q

The PNS contains the

A

peripheral nerves (cranial & spinal)
Neuromuscular junction

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4
Q

What embryonic layer makes the nervous system

A

ectoderm

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5
Q

what embryonic layer makes the notochord

A

mesoderm

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6
Q

What does the notochord become

A

nucleus pulposus of intervertebral disc

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7
Q

what does the alar plate give rise to?

A

dorsal horn (sensory)

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8
Q

what does the basal plate give rise to?

A

ventral horn (motor)

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9
Q

where is the subarachnoid space located in relation to the layers of the dura

A

between the dura mater and arachnoid mater

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10
Q

what is found in the subarachnoid space

A

CSF

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11
Q

what is the cerebellomedullary cistern and what is its clinical significance?

A

space at C1 where the SAS is expanded and spinal taps are performed

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12
Q

where is the CSF produced?

A

choroid plexus

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13
Q

summarize primary neuralation

A
  1. ectoderm thickens to make the neural plate
  2. neural groove appears
  3. folds generate the neural tube and neural crest cells
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14
Q

summarize secondary neuralation

A
  1. caudal neuropore closes
  2. solid tube of ectodermal cells develop cavities - producing a hollow tube that connects with the central canal
  3. sacral/caudal cord segments develop here
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15
Q

What are the 3 zones of the early spinal cord (outermost to innermost)

A
  1. marginal layer
  2. mantle layer
  3. ventricular zone
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16
Q

the dorsal median sulcus deals with _____ inputs

A

sensory

17
Q

the ventral median fissure deals with ____ inputs

A

motor

18
Q

Describe the locations of the lateral horn

A

T1-L4/5 (sympathetic)
S1-3 (parasympathetic)

19
Q

What do neural crest cells produce

A

sympathetic postganglionic neurons
adrenal medulla
melanoblasts
Schwann cells

20
Q

What is Spina Bifida

A

failure of fusion of the vertebral arch

21
Q

Spina Bifida Occulta

A

bone missing

22
Q

Spina Bifida Aperta

A

meninges protrude (meningocele)
meninges + spinal cord (meningomyelocele)

23
Q

dura mater

A

very tough
fused to the skull and C1 periosteum
covers optic nerve

24
Q

arachnoid mater

A

fused to dura mater
delicate trabecular projections to pia mater
“buffer zone”

25
Q

pia mater

A

closely apposed to CNS
adjacent to glia limitans
thickens bilaterally to form denticulate ligaments to suspend spinal cord

26
Q

What is the blood-brain barrier

A

a barrier between the plasma in CNS vessel and ECF made of endothelial tight junctions, pericytes, and astrocytic endfeet

27
Q

what two locations can be used to sample CSF

A
  1. cerebellomedullary cistern
  2. lumbar cistern
28
Q

Meningitis

A

inflammation of meninges

29
Q

subdural abscess

A

caused by bacterial infections and can cause separation of dura from skull

30
Q

Meningiomas develop from

A

arachnoid cap cells

31
Q

Describe the ventricular system

A

2 lateral ventricles
3rd ventricle
4th ventricle

32
Q

Lateral ventricles

A

each has choroid plexus
connect via interventricular foramen to 3rd

33
Q

3rd ventricle

A

contains extensions of lateral choroid plexi
surrounds interthalamic adhesion
connects to 4th via mesencephalic aqueduct

34
Q

4th ventricle

A

lies over pons and medulla
has paired choroid plexi
flows into central canal + SAS

35
Q

choroid plexus

A

cluster of villi projecting into the ventricle
CSF producing

36
Q

Arachnoid villi ____ with increasing CSF pressure and ____ drainage

A

expand; increase