Lecture 38 - Parasympathetic Flashcards
Where do cranial nerves CNI and CNII originate
cerebrum
where do cranial nerves CNIII - XII
brainstem
Name the cranial nerves I - XII
- olfactory
- optic
- oculomotor
- trochlear
- trigeminal
- abducens
- facial
- vestibular cochlear
- glossopharyngeal
- vagus
- accessory
- hypoglossal
what is a mnemonic to help remember the cranial nerves
Oh! Oh! Oh!
To Touch And Feel
Very Good Velvet
Ah Heaven
what is a mnemonic to help remember the function of cranial nerves
Some Say Marry Money But My Brother Says Big Brains Matter More
how are functions of cranial nerves classified
- Sensory
- Motor
- Both
What cranial nerves have parasympathetic fibers
oculomotor (3)
facial (7)
glossopharyngeal (9)
vagus (10)
what is the function of CN1
smell
what is the function of CN2
vision
what is the function of CN3
eye movement (up/down, open eyelid, pupil constriction)
what is the function of CN4
moves eye down and inwards
what is the function of CN5
sensation to the face, mastication
what is the function of CN6
moves eye laterally
what is the function of CN7
facial expression, taste (anterior 2/3), glands
what is the function of CN8
hearing, balance
what is the function of CN9
taste (posterior 1/3), swallowing, salivary glands
what is the function of CN10
parasympathetic supply to eye, heart, gut, lungs, larynx
what is the function of CN11
rotate the head and lift shoulders
what is the function of CN12
supply tongue muscles
T/F: both pre and post-ganglionic parasympathetic fibers use acetylcholine as a neurotransmitter
TRUE
what is the role of the parasympathetic system
maintenance functions
- “rest and digest”
- D division
what functions are encompassed by the D division
digestion, diuresis, defecation
what does “SLUDD” mean
S - salivation
L - lacrimation
U - urination
D - digestion
D - defecation
why are SLUDD actions typically seen in toxic cases
due to an overproduction of acetylcholine
what are the cholinergic receptors and their subdivisions
nicotinic: ionotropic
muscarinic: G-coupled, M1-M5
What is the location and effect of:
M1
location: CNS + stomach
effect: Gq, depolarization, H+ secretion
What is the location and effect of:
M2
location: heart, lungs
effect: Gi, bradycardia, AV block, bronchoconstriction
What is the location and effect of:
M4
location: CNS, heart
effect: Gi signaling
What is the location and effect of:
M3
location: smooth muscle, salivary gland, + CNS
effect: Gq, bronchoconstriction, salivation, vasodilation
What is the location and effect of:
M5
location: CNS
effect: Gq signaling
parasympathomimetic
mimics parasympathetic system
parasympatholytic
opposes parasympathetic action
direct effect
agonist or antagonist of the receptor
indirect effect
nonreceptor related
summarize the parasympathetic effects on the eye
- constrict pupils
- lens bulge
- lacrimation
summarize the parasympathetic effects on the heart
- bradycardia, negative chronotropic
- negative inotropy (contraction)
- negative dromotropy (decreased AV node conduction)
T/F: The parasympathetic system increases GI function
TRUE - increased secretion (insulin, bile, etc.), motility
summarize the effect of the parasympathetic system on the UGT
- bladder contraction
- releasing urethral sphincter
- promote voiding
summarize the effect of the parasympathetic system on the reproductive systems
vasodilation
increased vaginal lubrication
