Lecture 2 - Cell Biology 1 Flashcards
Describe the structural hierarchy of the body
Atoms - molecules - organelles - cells - tissues - organs - organ systems - organism
A Magic Orange Cat Turned Over Only Oranges
Atoms - molecules - organelles - cells - tissues - organs - organ systems - organism
What do organelles allow the cell to do
grow, divide, and specialize
What organism is the “city hall” of the cell
Nucleus
Properties of the nucleus
responsible for DNA storage and transcription
within nuclear envelope
What is the “powerhouse”/electrical grid of the cell
Mitochondria
Properties of the Mitochondria
ATP production
of mitochondria represent metabolic demand
self-replicating
What is the “primary production plant” of the cell
Rough Endoplasmic Reticulum
Properties of Rough ER
contain ribosomes for protein synthesis
continuous w/ nuclear envelope
What is the “accessory power plant” of the cell
Smooth Endoplasmic Reticulum
Properties of the Smooth ER
Lipid and steroid synthesis
detoxification of the cell
What cell has abundant smooth ER
Liver
What is the “post office” of the cell
Golgi Apparatus
Properties of the Golgi Apparatus
packages proteins in vesicles
determines destination based on sugar “tag” - important for specialization
What is the “recycling center” of the cell
Lysosome
Properties of the lysosome
hydrolyzes substances that cross the cell membrane
What is important about the enzymes in lysosomes
the enzymes need a lower pH to be activated whereas the cell environment is more neutral - protective
What is the “thrift store” of the cell?
Peroxisome
Properties of the peroxisome
Degrades fatty acids and reactive oxygen species
Functions of the cell membrane
1 - Exclusion
2 - Consumption
3 - Excretion
4 - Communication
What are the primary components of the plasma membrane
1 - phospholipids
2 - cholesterol
3 - proteins
4 - carbohydrates
Cholesterol
Interspersed in phospholipid belayer
Maintains fluidity of membranes in fluctuating temperatures
What two categories are membranes divided into
Integral and peripheral
Integral proteins
At least one hydrophobic region which anchors within membrane
Transmembrane passes all the way through
Peripheral proteins
Inside or outside
Facilitate communication and coordination
Carbohydrates found on the cell membrane are called
Glycolipids and glycoproteins
What are carbohydrates on the cell membrane important for
Intercellular communication and recognition
What are the two categories of cellular transport
Passive (no energy needed) and active (energy required)
Simple diffusion
Movement of molecules down their concentration across diets the cell membrane
Osmosis
Diffusion of water molecules from low solvent concentration to high solvent concentration
Facilitated diffusion
Requires a membrane transport channel protein
Primary active transport
Direct utilization of ATP to move particles against their concentration gradient
Sodium-potassium pump
Secondary active transport
Using the energy of one particle down its gradient to power transport of a particle against its gradient
Symporters
Both molecules move in same direction
Antiporter
Move molecules in opposite directions
Functions of cytoskeleton
1 - Supporting membrane and providing the cell its shape
2 - arranging organelles
3 - provides infrastructure for vesicular movement
4 - allows cell to move
Microfilaments
Edge of cytoplasm
Cellular movement, structure, and tracks for transport
Intermediate filaments
Specialized to bear tension and maintain shape of cell
Microtubules
Largest fiber
Resist compression forces, aid in vesicular transport, form spindle in mitosis
Types of cell adhesion
1 - gap junctions
2- tight junctions
3 - desmosomes
Gap junction
Transmembrane proteins aligned between two adjacent cells
Forms aqueous channel
Ex: heart muscle cells
Tight junctions
Connection points between cells that create a waterproof barrier
Ex: bladder lining
Desmosomes
Spot welds
Complexes of proteins that allow tissue to stretch w/o tearing
Germ layers from innermost to outermost
Endoderm, mesoderm, ectoderm
Endoderm
Inner gi and pulmonary
Mesoderm
Muscle + connective tissues