Lecture 17: Hemodynamics (Hayward)

Question 1

which vessels have large elastic layer? why?

Answer 1

Arteries. Stores energy so you can continuously push blood through CV when heart is not actively pushing it through

Question 2

Flow formula

Answer 2

F = (P1-P2)/R Q=F=Flow

Question 3

Cardiac output formula

Answer 3

CO = (MAP-RAP)/TPR TPR = resistance in entire vascular tree ***MEMORIZE

Question 4

Sickle cell anemia

Answer 4

fibrinogen in RBCs increases, decreasing their flexibility and results in disturbances in regional blood flow

Question 5

increasing radius of tubes–> TPR

Answer 5

decreases

Question 6

Increasing number of tubes in parallel –> TPR

Answer 6

decreases

Question 7

Increasing tube length –> TPR

Answer 7

increases

Question 8

Poiseuille’s Law

Answer 8

describes effect of length, radius, number of tubes, etc. effect resistance

Question 9

Tubes in parallel generally have _____ resistance to tubes in series

Answer 9

lower

Question 10

MAP formula**

Answer 10

MAP = CO * TPR

Question 11

velocity def. and formula

Answer 11

distance a fluid travels per unit time. V=Q/A

Question 12

increased cross-sectional area –> velocity

Answer 12

decreases

Question 13

in laminar flow shear stress on vascular walls is prop. to

Answer 13

rate of flow

Question 14

ONLY place where energy can be added to vasculature

Answer 14

heart

Question 15

2 components of total energy stored in vasculature

Answer 15

1) KE (forward projecting)

2) PE (lateral projecting)

Question 16

anemia –> turbulent flow

Answer 16

increases

Question 17

Reynold’s number

Answer 17

predicts turbulence. Re=VDdensity/viscosity

Question 18

high blood velocity –> turbulent flow

Answer 18

increases

Question 19

larger vessel size –> turbulent flow

Answer 19

increases

Question 20

Bernoulli’s Principle

Answer 20

total energy at one area in a closed system must equal total energy in another area. Achieved by Pressure/volume/area/velocity relationships

Question 21

velocity ______ as venous blood comes out of capillaries and heads back to heart

Answer 21

increases (but at a lower velocity than it left heart)

Question 22

aortic stenosis –> lateral pressure

Answer 22

decreases

Question 23

aortic stenosis –> coronary filling

Answer 23

decreases. Harder time getting blood out and storing energy

Question 24

aneurysm

Answer 24

abnormal dilation of blood vessel walls resulting from disease of the vessel wall. weak vessel wall

Question 25

aneurysm –> pressure on vessel wall

Answer 25

increases (due to increased vessel diameter)