Lecture 16: The Heart as a Pump (Hayward) Flashcards
stroke volume
volume of blood pumped from one ventricle of the heart with each beat. Amt of blood that leaves ventricle from when aortic valve opens to closes
Frank Starling Mechanism
states that the stroke volume of the heart increases in response to an increase in the volume of blood filling the heart (the end diastolic volume) when all other factors remain constant.
amount of LV filling is a fx of:
how much volume started in LV and the time for filling before AV valves close
preload is a ______, while afterload is a ______
volume; pressure
3 factors that affect cardiac performance **
preload (diastolic filling), afterload (aortic pressure), inotropic state (contractility)
increased afterload –> stroke volume, cardiac output
decreases both
increased contractiliy –> cardiac performance
increases
Key modulators of cardiac output
Contractility, preload, afterload
increased contractility —> stroke volume
increases
increased preload –> stroke volume, cardiac output
increases both
increased HR –> cardiac output
increases