Exam 5: Growth Hormone Flashcards
What are the functions of growth hormone?
Anabolic
Lipolytic
Diabetogenic
What are the anabolic functions of GH?
Increase protein synthesis
Increase bone and soft tissue
What does GH result in?
Protein anabolism
What does decreased CHO utilization by GH cause?
Insulin resistance
What does insulin-like growth factor-1 do?
Mediates growth-promoting effects of GH
What is insulin-like growth factor-1 synthesized by?
Liver, which is directly stimulated by GH
What is the anabolic function of insulin-like growth factor-1?
Stimulates AA uptake and activation of enzymes for protein synthesis
What are IGF and GH concentrations like during growth in large breeds?
IGF: same
GH: Increased and persists longer
What are IGF and GH concentrations like during growth in small breeds?
IGF: same
GH:Increased for a shorter duration
What are IGF and GH concentrations like during adulthood in large breeds?
GH: same
IGF: higher
What are IGF and GH concentrations like during adulthood in small breeds?
GH: same
IGF: lower
What is the stimulus for GH release in dogs? Where does it stimulate GH from?
Progestogens
Mammary tissue