Exam 5: Growth Hormone Flashcards

1
Q

What are the functions of growth hormone?

A

Anabolic
Lipolytic
Diabetogenic

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2
Q

What are the anabolic functions of GH?

A

Increase protein synthesis

Increase bone and soft tissue

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3
Q

What does GH result in?

A

Protein anabolism

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4
Q

What does decreased CHO utilization by GH cause?

A

Insulin resistance

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5
Q

What does insulin-like growth factor-1 do?

A

Mediates growth-promoting effects of GH

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6
Q

What is insulin-like growth factor-1 synthesized by?

A

Liver, which is directly stimulated by GH

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7
Q

What is the anabolic function of insulin-like growth factor-1?

A

Stimulates AA uptake and activation of enzymes for protein synthesis

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8
Q

What are IGF and GH concentrations like during growth in large breeds?

A

IGF: same
GH: Increased and persists longer

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9
Q

What are IGF and GH concentrations like during growth in small breeds?

A

IGF: same
GH:Increased for a shorter duration

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10
Q

What are IGF and GH concentrations like during adulthood in large breeds?

A

GH: same
IGF: higher

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11
Q

What are IGF and GH concentrations like during adulthood in small breeds?

A

GH: same
IGF: lower

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12
Q

What is the stimulus for GH release in dogs? Where does it stimulate GH from?

A

Progestogens

Mammary tissue

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