Exam 1 – Dr. Thomason: Leukocytes Flashcards
What are the 2 broad categories of leukocytes?
Polymorphonuclear
Mononuclear
What are the polymorphonuclear leukocytes?
Neutrophils
Eosinophils
Basophils
What are the mononuclear leukocytes?
Monocytes
Lymphocytes
What are leukocytes involved with?
Immunity
What do granulocytes and monocytes do?
Protect against invading organisms and allergies
What do lymphocytes do?
Regulation of the immune system
Where are leukocytes formed?
Bone marrow
Where do most lymphocytes continue to mature and replicate?
Lymphoid tissue (lymph node and spleen)
What are monocytes and neutrophils derived from?
Common progenitor cell (CFU-GM)
What do T and B lymphocytes have a significant role in?
Regulation of immunity
What is the most numerous and most important cell?
Neutrophils
What do neutrophils do?
Phagocytize microorganisms
Eliminate microorganisms via intracellular vesicles
What do neutrophils contain?
Antimicrobial substances in granules
What 2 bone marrow compartments do neutrophils develop in?
Proliferation or mitotic compartment (20%)
Maturation and storage compartment (80%)
What does the release of immature neutrophils lead to?
Left shift