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My Flashcards Year 2 > Endo- thyroid disorders > Flashcards

Endo- thyroid disorders Flashcards

1
Q

thyrotoxicosis

A

the clinical, physiological and biochemical state arising when tissues are exposed to excess thyroid hormone

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2
Q

hyperthyroidism

A

refers specifically to the conditions in which overactivity of the thyroid gland lead to thyrotoxicosis

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3
Q

most common cause of hyperthyroidism

A

Graves disease

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4
Q

graves disease more common in females/males

A

females (10:1)

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5
Q

in graves disease, which receptor antibodies stimulate the thyroid

A

anti-TSH

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6
Q

general symptoms of hyperthyroidism

A

weight loss despite increased appetite
frequent, loose bowel movements
sweating and heat intolerance
goitre- diffuse, toxic

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7
Q

goitre

A

enlargement of the thyroid gland

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8
Q

CVS symptoms of hyperthyroidism

A

increased pulse rate
palpitations, AF
rarely cardiac failure

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9
Q

what is graves eye disease associated with

A

smoking

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10
Q

what produces the TSH

A

the pituitary gland (located in the brain)

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11
Q

primary hyperthyroidism hormones

A

TSH low
T3/T4 high

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12
Q

thyroid autoantibodies in graves disease

A

TSH receptor antibody
Anti-TPO antibody
Anti-thyroglobulin antibody

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13
Q

1st line medical management in graves disease

A

carbimazole

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14
Q

thyroid storm

A

rapid deterioration of hyperthyroidism with:
hyperpyrexia
severe tachycardia
extreme restlessness
cardiac failure
liver dysfunction

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15
Q

immediate symptomatic relief of thyrotoxicosis symptoms

A

beta blockers

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16
Q

preferred antithyroid medication in first trimester of pregnancy

A

PTU

17
Q

hypothyroidism

A

results from any disorder that results in insufficient secretion of thyroid hormones from the thyroid gland

18
Q

symptoms of hypothyroidism

A

tiredness/malaise
weight gain, despite < appetite
cold intolerance
< sweating
constipation
bradycardia

19
Q

primary hypothyroidism hormones

A

TSH high
T4 and T3 low

20
Q

Thyroid antibodies in autoimmune hypothyroidism

A

anti-TPO antibody
antithyroglobulin
TSH receptor antibody

My Flashcards Year 2 (27 decks)

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