Child health- endo Flashcards

1
Q

growth hormone stimulates the release of what and by what?

A

insulin-like growth factor 1 (IGF-1)
by the liver

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2
Q

where in the body produces growth hormone

A

pituitary gland

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3
Q

what is empty sella syndrome

A

condition where pituitary gland is underdeveloped or damaged

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4
Q

clinical features of growth hormone deficiency at birth/in neonates

A

micropenis (in males)
hypogylcaemia
severe jaundice

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5
Q

clinical features of growth hormone deficiency in older infants and children

A

poor growth, usually stopping or severely slowing by age 2-3
short stature
slow development of movement and strength
delayed puberty

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6
Q

investigations for growth hormone deficiency

A

growth hormone stimulation test

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7
Q

management of growth hormone deficiency

A

daily subcutaneous injections of growth hormone (somatropin)

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