Endo- thyroid and pituitary drugs

Question 1

first line drug used in hyperthyroidism

Answer 1

carbimazole

Question 2

mechanism of action of carbimazole

Answer 2

inhibition of TPO therefore blocking thyroid hormone synthesis

Question 3

rare but serious side effect of carbimazole

Answer 3

agranulocytosis- presents with fever, sore throat, signs of infection

Question 4

preferred antithyroid medication in first trimester of pregnancy

Answer 4

PTU