Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

SL22044 Neuroscience > Amine NTs second half 1.0 > Flashcards

Amine NTs second half 1.0 Flashcards

1
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Where is the tubero-infundibular system located?

A

Hypothalamus to the pituitary gland

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What type of receptors does dopamine act at?

A

GPCRs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the tubero-infundibular system involved in?

A

Endocrine function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the same between dopamine and noradrenaline?

A

Their inactivation (reuptake and degradation)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which pathway degenerates in parkinsons?

A

Nigro-striatal pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which NT does NMDA increase?

A

5HT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Where does 5HT arise from?

A

Raphe nuclei

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Where does 5HT project?

A

Forebrain (cerebral cortex, cerebellum), spinal cord

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what are the 5HT neurons in the spinal cord involved in?

A

pain perception and pain regulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

5HT dysfuncion is associated with?

A

depression, sleepy, abnormal feeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Increased activity of 5HT systems in regard to food?

A

Loss of appetite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Decreased activity of 5HT systems in regard to food?

A

Gain of weight

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is tryptophan taken up via?

A

transporters

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

First thing to happen to tryptophan in 5ht synthesis?

A

Conversion to 5-hydroxytryptophan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which enzyme catalyses the conversion of tryptophan to 5-hydroxytryptophan?

A

Tryptophan hydroxylase

17
Q

What is 5-hydroxytryptophan converted to?

A

5-hydroxytryptamine

18
Q

What enzyme catalyses the formation of 5-hydroxytryptamine

A

5-hydroxytryptophan carboxylase

19
Q

What happens to 5-hydroxytryptamine after synthesis?

A

taken up by vesicles

20
Q

Inactivation of 5ht?

A

Reuptake and degradation

21
Q

5ht degredation enzyme?

A

Monoamine oxidase

22
Q

What is unique ab 5HTs reuptake transporters?

A

They are specific to 5HT

23
Q

Where does ACh project to from the magnocellular neurons?

A

cortex/limbic system

24
Q

Types of ACh receptor?

A

Ionotropic and GPCR

25
Q

Ionotropic ACh receptor?

A

Nicotinic

26
Q

GPCR ACh receptor?

A

Muscarinic

27
Q

Role of ACh?

A

Arousal, sleep, waking

28
Q

Initial molecule used in ACh formation?

A

Choline

29
Q

How is ACh formed?

A

Choline combines with acetyl-CoA

30
Q

enzyme catalysing ACh formation?

A

Choline acetyltransferae

31
Q

Which enzyme breakd down ACh?

A

Acetylcholineesterase

32
Q

WHat is produced as a result of ACh breakdown?

A

Free choline, acetic acid

33
Q

what is taken up after ACh degredation?

A

Free choline

34
Q

Treatment for alzheimers regarding ACh?

A

Targets acetylcholineesterase to prevent ACh degradation

SL22044 Neuroscience (34 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions