Wound Management Flashcards
what are the three phases of wound healing?
inflammation
tissue formation
tissue remodeling
what are the three early phase phenomena of wound healing?
epithelialization
granulation tissue formation
contraction
when does epithelialization of a wound start?
within hours of injury
when does granulation tissue form?
3-4 days post injury
what does granulation tissue do?
lends surface for epithelialization and is resistant to infection
what drives contraction?
cytokines: PDGF, TGF-beta
myofibroblasts from the dermis attach to collagen matrix
what are the options for the clinical management of wounds?
primary closure
delayed primary closure
secondary closure
tertiary closure
what is the primary purpose of debridement?
remove foreign material, dead tissue, and bacterial contaminants
what is the negative of topical antibacterial or antiseptic creams?
may slow healing
why would you apply a plastic layer to a wound?
prevents spread of debris or bacteria from adjacent skin into wound
what should you do with proud flesh?
surgically remove excess granulation tissue
may need repeated trimming
what are the advantages of split thickness grafts?
neovascularization occurs faster
less “all or nothing phenomenon”
abundance of donor sites
donor site heals fast
