Disorders of the Newborn Foal Part I Flashcards

1
Q

what are the conditions of the <24 hour old foal?

A

prematurity
dysmaturity
the “dummy foal”
neonatal maladjustment syndrome
sepsis

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2
Q

how is incomplete ossification of the cuboidal bones graded?

A

1-4 based on severity

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3
Q

foals born before ____________ are unlikely to survive and will not be athletes

A

300 days

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4
Q

what is dysmaturity?

A

delivered at full term but show characteristics of prematurity
most commonly due to placental insufficiency

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5
Q

how common is perinatal asphyxia syndrome?

A

1-2% of births

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6
Q

what happens in the delayed phase of perinatal asphyxia syndrome?

A

hyperemia and cytotoxic edema
Ca enters cells and leads to activation of enzymes

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7
Q

what does therapy of perinatal asphyxia syndrome depend on?

A

severity of perinatal asphyxia syndrome

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8
Q

what is the prognosis of perinatal asphyxia synrome?

A

good: up to 80% survive and achieve athletic function

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9
Q

which foals with perinatal asphyxia syndrome have poorer outcomes?

A

those that exhibit seizure activity within the first 24 hours of life
septic foals

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10
Q

when should you perform a madigan foal squeeze?

A

for foals with neonatal maladjustment syndrome

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11
Q

what is sepsis?

A

systemic inflammatory response syndrome in the presence of suspected or proven infection

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12
Q

what is the most common pathogen in neonatal sepsis?

A

E. coli

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13
Q

what can be seen on bloodwork in a septic foal?

A

leukopenia
azotemia common
hypoglycemia
hypoxemia/hypercapnia
hyperlactatemia
increased serum amyloid A
positive blood culture

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14
Q

what therapy can you perform for a septic foal?

A

antimicrobials
fluid therapy
hyperimmune plasma
supportive care

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15
Q

what are some predictors for a septic foal?

A

prematurity
specific sites of infection
sepsis score
temperature
WBC count

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16
Q

should you bottle feed a septic foal?

A

never

17
Q

what is prematurity?

A

unreadiness for birth
delivery before 320 days- variable
physical and functional

18
Q

what are the physical signs of prematurity?

A

small body size and low birth weight
prominent rounded forehead
silky hair coat
entropion
floppy ears
flexor tendon laxity
incomplete ossification of the cuboidal bones

19
Q

how is incomplete ossification of the cuboidal bones treated?

A

reduce time standing and activity
maybe full limb bandages

20
Q

what are the functional effects of prematurity?

A

weakness
difficulty standing
impaired thermoregulation
abnormal glucose metabolism
cardiovascular dysfunction
respiratory dysfunction
gastrointestinal dysfunction
renal dysfunction

21
Q

what are the survival rates of premature foals?

A

up to 80%

22
Q

how can you prevent prematurity?

A

close monitoring of pregnancy
early treatment of placentitis
avoid induction of parturition

23
Q

what can cause a “dummy foal”?

A

perinatal asphyxia syndrome
neonatal encephalopathy
hypoxic ischemia encephalopathy
dummy foal
wanderer
barker foal

24
Q

what is perinatal asphyxia syndrome?

A

hypoxia of tissues occurring during parturition

25
Q

which organs are most sensitive to perinatal asphyxia syndrome?

A

brain
gastrointestinal tract
kidney

26
Q

what happens in the initial phase of perinatal asphyxia syndrome?

A

energy failure due to oxygen and glucose depletion

27
Q

what is therapy for perinatal asphyxia syndrome?

A

supportive care
maintain tissue perfusion
oxygen therapy
manage seizure activity
manage organ damage
therapeutic hypothermia?

28
Q

what is neonatal maladjustment syndrome?

A

foals which appear to be dummy foals but have no history of hypoxic event
often foals delivered very fast

29
Q

what is a madigan foal squeeze thought to do?

A

reset neurotransmitters

30
Q

what is the prognosis of neonatal sepsis?

A

50-60%

31
Q

what bacteria can cause neonatal sepsis?

A

gram negative or gram positive
E. coli, streptococci, Enterococcus, Actinobacillus, Enterobacter, staphylococci

32
Q

what goals should you aim to achieve with fluid therapy of a septic foal?

A

improved pulse quality and rate
correct clinical signs of dehydration
urine output
normalize PCV and lactate