Medical Management of Degenerative Joint Disease Flashcards

1
Q

what happens in the intimal layer of the synovium?

A

phagocytosis: type A synoviocytes
protein synthesis: type B synoviocytes

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2
Q

why are changes in synovial fluid properties a problem?

A

less effective boundary lubrication of soft tissues

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3
Q

what are some commonly used medications?

A

NSAIDs
corticosteroids
hyaluronan
nutriceuticals
orthobiologics

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4
Q

what does interleukin-1 do?

A

major mediator of cartilage degeneration and destruction

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5
Q

what are the indications for IRAP?

A

mild to moderate osteoarthritis
capsulitis/synovitis
post-arthroscopic exploration
OCD post-op
post septic arthritis?

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