Medical Management of Degenerative Joint Disease Flashcards
1
Q
what happens in the intimal layer of the synovium?
A
phagocytosis: type A synoviocytes
protein synthesis: type B synoviocytes
2
Q
why are changes in synovial fluid properties a problem?
A
less effective boundary lubrication of soft tissues
3
Q
what are some commonly used medications?
A
NSAIDs
corticosteroids
hyaluronan
nutriceuticals
orthobiologics
4
Q
what does interleukin-1 do?
A
major mediator of cartilage degeneration and destruction
5
Q
what are the indications for IRAP?
A
mild to moderate osteoarthritis
capsulitis/synovitis
post-arthroscopic exploration
OCD post-op
post septic arthritis?