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USMLE-Pathology-(Pathoma+ FA+UWorld) > Vulva Pathology Female Reproductive > Flashcards

Vulva Pathology Female Reproductive Flashcards

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USMLE® Step 1 flashcards
1
Q

Vulva lining epithelium ?

A

Squamous epithelium

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2
Q

Vulva contain skin and mucous of which anatomical external orhans of female ?

A
  1. Labia majora
  2. Labia minora
  3. Mons pubis
  4. Vestibule
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3
Q

Cystic dilation of the bartholin gland ?

A

Bartholin cyst

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4
Q

Cause of bartholin cyst ?

A
  1. Inflammatioon
  2. Obstruction of gland
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5
Q

Hallmark of HPV infected cells in condyloma ?

A

koilocytes
koilocytic changes

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6
Q

Location of bartholin gland ?

A

Each side of vaginal canal
= produce mucous like fluid
=drains via ducts into the lower vestibule

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7
Q

Presentation of bartholin cyst ?

A
  1. Unilateral
  2. Painful
  3. Cystic lesion at the lower vestibule
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7
Q

Progression of condyloma ?

A

Carcinoma
less risk - type 6/11 HPV

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8
Q

Warty neoplasm of vulvular skin often large ?

A

Condyloma

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9
Q

Causes of condyloma ?

A
  1. HPV 6/11 -condyloma acuminatum
  2. Secondary syphilis - C latum

Pathoma-137

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10
Q

Presentation of lichen sclerosis ?

A
  1. Leukoplakia = White patch
  2. Parchment like vulvar skin
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10
Q

Lichen sclerosis characterized by —

A
  1. Epidermis = Thinining
  2. Dermis = Fibrosis / sclerosis

137

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11
Q

Common whom ?

Lichen sclerosis

A

Postmenopausal women

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11
Q

Ca association of lichen sclerosis ?

A

Benign

Squamous Cell Ca

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12
Q

Lichen simplex chronicus cause ?

A

Squamous epithelium of vulva= Hyperplasia

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12
Q

Presentation of lichen simplex chronicus ?

A
  1. Leukoplakia=White patch
  2. Leathery vulvar skin
13
Q

Association of lichen simplex chronicus ?

A
  1. Scratching
  2. Chronic irritation
14
Q

Ca association of LSC ?

A

Benign

no chance of Squmous cell Ca

15
Q

Lichen sclerosis VS
Lichen Simplex Chronicus ?

A
  1. LS=Parchment like vulvar skin
  2. LSC=Lethery vulvar skin
16
Q

Carcinoma of vulva ?

A

Squamous cell of vulva

17
Q

Causes of vulvar carcinoma ?

A
  1. HPV cause - HPV-16/18
  2. Non-HPV - Long standing lichen sclerosis
18
Q

VIN characteristics?

A
  1. Dysplastic lesion
  2. Koliocytic change
  3. Disordered cellular maturation
  4. Nuclear atypia
  5. inc mitotic activity

138

18
Q

Vulvar carcinoma arise from which neoplasia ?

A

Vulvar intraepithelial neoplasia
VIN

19
Q

Presentation of extramammary paget disease ?

A
  1. Erythematous
  2. Pruritic
  3. Ulceeated vulvar skin
19
Q

Presenation of paget d in skinn?

A

Carcinoma in situ
No underlying carcinoma

20
Q

Non-HPV vulvar Ca seen in —

A

Elderly women - >70yr

20
Q

Malignant epithelial cells in the epidermis of the vulva ?

A

Extramammary paget disease

21
Q

Paget disease in nipple vs Vulva ?

A
  1. PD in vulva = No underlying carcinoma
  2. PD in nipple = Underlying carcinoma
22
Q

PD in vulva should be distinguish from ?

A

Melanoma

23
Q

Melanoma vs PD vulva

A
  1. PD in vulva - PAS+ Keratin+ S-100-
  2. Melanoma- PAS- Keartin- S-100+

138

USMLE-Pathology-(Pathoma+ FA+UWorld) (75 decks)

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