Hodgkin Lymphoma Flashcards
1
Q
Proliferation of which cell in HL ?
A
Reed sternberg cell
2
Q
Surface marker in HL ?
A
CD15
CD30
3
Q
Histo slide in HL ?
A
Owl eyed nuclei
4
Q
Most common type of subtype of HL ?
A
Nodular sclerosis
5
Q
Reed sternberg cells of HL secretes —
A
Cytokines
6
Q
Presentation of nodular sclerosis ?
A
- Enlarge cervical or mediastinal lymph node
- Young adult
- Female
7
Q
Effects of RS cells in HL ?
A
- B symptoms - fever chills weight loss night sweat
- May lead to fibrosis
- Attract reactive plasma cell , lymphocytes , macrophage eosiniophils
8
Q
Histo-Bands of sclerosis >
A
Nodular sclerosis
9
Q
RS cells presentation in HL –NS ?
A
Lake like space - Lacunar cells
10
Q
Best prognosis in HL >?
A
Lymphocyte rich L
11
Q
Mixed cellularity type is mixed with ?
A
Abundant eosinophills = IL5
63
12
Q
Most aggressive HL ?
A
Lymphpcyte depleted HL
13
Q
Lymphpcyte depleted HL whom ?
A
- HIV patients
- Elderly
