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USMLE-Pathology-(Pathoma+ FA+UWorld) > Ovarian Tumors > Flashcards

Ovarian Tumors Flashcards

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USMLE® Step 1 flashcards
1
Q

Ovarianc cell types ?

A
  1. Surface epithelium
  2. Germ cells
  3. Sex cord storma

PATHOMA-145

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2
Q

SECa derived from /

A

Coelomic epithelium

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2
Q

Most common type ovarian cancer ?

A

Surafce epithelium cancer

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3
Q

Lining of ovary ?

A

Coelomic epithelium

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3
Q

Benign tumor of surface peithelium cancer of ovary >???

A

Cystadenoma

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4
Q

Cystadenoma common in —

A

Premanopausal women

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4
Q

Coelomic epithelium derivatives ?

A
  1. Fallopian tube-Serous cell
  2. Endometrium
  3. Endocervix
  4. Mucinous cells
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5
Q

Common subtypes of ovarian surface epithelial cancer ?

A
  1. Serous tumor =Watery fluid
  2. Mucinous tumor = Mucus like fluid
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6
Q

Cystadenoma cyst type >

A

Single + Flat + Simple

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7
Q

Malignant tumor of surface epithelium of ovary ?

A

Cystadenocarcinoma

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8
Q

Cystadenocarcinoma common in -

A

Postmenopausal womnen

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9
Q

Cystadenocarcinoma cyst type-

A

Complex cyst
Shaggy lining

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10
Q

Which mutation ?

A

BRCA1

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10
Q

BRCA1 carrier have –

A

Prophylactic salpingo-oophorectomy + prophylactic mastectomy

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11
Q

Less common subtypes of surface epithelium ovarian cancer ?

A
  1. Endometroid tumor
  2. Brenner tumors
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11
Q

Bladder like epithelium Ca + Benign = ?

A

Brenner tumors

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12
Q

Brenner tumor Histo ?

A

Coffee bean nuclei on biopsy

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13
Q

Cystic teratoma fetal tissue ?

A

skin hair bone cartilage gut thyroid

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13
Q

Serum marker for ovarian cancer ?

A

CA-125

14
Q

Presentation of surface epithelium ovarian cancer ?

A
  1. Vague abdominal symptoms
  2. Pain
  3. Fullness
  4. Sign of compression
  5. Urinary frequency
15
Q

2nd most common ovarian cancer is –

A

Germ cell tumors

15
Q

Tumor subtypes mimic tissues normally produced by germ cells —-

A
  1. Fetal tissue = Cystic teratoma
  2. Oocytes = Dysgerminoma
  3. Yolk sac = Endodermal sinus tumor
  4. Placental tissue = Choriocarcinoma
16
Q

Cystic teratoma + Thyroid tissue = ?

A

Struma ovarii

146

17
Q

Fried egg appearance in Histo ?

A

Dysgerminoma

17
Q

Dysgerminoma testicular counterpoint ?

A

Seminoma

18
Q

Indication of Dysgerminoma ?

A

inc LDH

18
Q

Dysgerminoma composed of —

A
  1. Large cells
  2. Clear cytoplasm
  3. Central nuclei= Represents oocytes
19
Q

Placental tissue germ cell ovarian cancer name ?

A

Choriocarcinoma

19
Q

Malignant tumor that mimic yolk sac is –

A

Endodermal sinus tumor

19
Q

Histology of endodermal sinus tumor ?

A

Schiller duval bodies

20
Q

EST indication ?

A

inc serum AFP

20
Q

Choriocarcinoma composed of -

A
  1. Cytotrophoblasts

2.Syncytiotrophoblasts

21
Q

Hematogenous spread tumor ?

A

Choriocarcinoma

21
Q

Beta HCG produced by –

A

Syncytriotrophoblasts

21
Q

Malignant tumor composed of large primitive cells-

A

Embryonal carcinoma

21
Q

Choriocarcinoma indication ?

A

inc Beta-HCG

22
Q

Neoplastic proliferation of granulosa and theca cell ==

A

G-theca cell tumor =Maliganant

23
Q

Features of sex cord stromal tumors ?

A
  1. Prior to puberty
  2. Precocious puberty
  3. Menorrhagia
  4. Metrorrhagia
  5. Postmenopause -most common
  6. Endometrial hyperplasia with
24
Q

Histo of granulosa theca cell sex cordnstromal tumor = ?

A

Call exner bodies
=Cell sourrounding bodies filled with pink material

25
Q

Reinke crystals ?

A

Sertoli leydig cell tumor

26
Q

Benign tumor of fibroblasts=n?

A

Fibroma

27
Q

Association of fibroma ?

A
  1. Pleural effusion
  2. Ascites
  3. Meigs syndrome
28
Q

Fate of sertoli leydig cell tumor ?

A
  1. Androgen inc
  2. Hiruitism
  3. Virilization
29
Q

Krukenberg tumor ?

A

Metastatic mucinous tumor that involves both ovaries

30
Q

Krukenberg tumor association ?

A

Metastatic gastric carcinoma - diffuse type

31
Q

Mucinous tumor of the appendix - metastasis to ovary = ?

A

Pseudomyxoma peritonei

Mucus in the peritoneum

PATHOMA-147

USMLE-Pathology-(Pathoma+ FA+UWorld) (75 decks)

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