Vagina Pathology Female Genitial Flashcards

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1
Q

Vagina lining epithelium ?

A

non-keratinizing squamous epithelium

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2
Q

Increased risk of which women
vaginal adenosis ?

A

Exposed to DiEthylStilBestrol DES in utero

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2
Q

Development of vagina ?

A
  1. uper 2/3 = Mullerian duct
  2. lower 1/3 = urogeenital sinus
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3
Q

Vaginal adenosis ?

A

Focal persistance of columnar epithelium in the upper vagina

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4
Q

Tx of adenocarcinoma ?

A

Stop of DES use

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4
Q

Complication of DES associated vaginal adenosis ?

A

Clear cell adenocarcinoma

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5
Q

Embryonal rhabdmyosarcoma ?

A

Malignant proliferation of immautre skeletal muscle

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6
Q

Vaginal carcinoma ?

A

High risk HPV

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6
Q

Presentation of ER ?

A

Grape like mass
=Sarcoma botryoides

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7
Q

Stain in ER ?

A

Z disk in desmin & myogenin
Rhabdomyoblast
Cytoplasmic cross striations

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8
Q

Precursor lesion ?

A

Vaginal intraepithelial neoplasia
VAIN

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9
Q

Spread of VAIN ?

A
  1. UPPER 2/3 = Iliac node
  2. Lower 1/3 = ingunal node
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