Vagina Pathology Female Genitial Flashcards
Vagina lining epithelium ?
non-keratinizing squamous epithelium
Increased risk of which women
vaginal adenosis ?
Exposed to DiEthylStilBestrol DES in utero
Development of vagina ?
- uper 2/3 = Mullerian duct
- lower 1/3 = urogeenital sinus
Vaginal adenosis ?
Focal persistance of columnar epithelium in the upper vagina
Tx of adenocarcinoma ?
Stop of DES use
Complication of DES associated vaginal adenosis ?
Clear cell adenocarcinoma
Embryonal rhabdmyosarcoma ?
Malignant proliferation of immautre skeletal muscle
Vaginal carcinoma ?
High risk HPV
Presentation of ER ?
Grape like mass
=Sarcoma botryoides
Stain in ER ?
Z disk in desmin & myogenin
Rhabdomyoblast
Cytoplasmic cross striations
Precursor lesion ?
Vaginal intraepithelial neoplasia
VAIN
Spread of VAIN ?
- UPPER 2/3 = Iliac node
- Lower 1/3 = ingunal node