Tetralogy Of Fallot Flashcards

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1
Q

Cause of FOT >?

UWorld

A

anterior and cephalad deviation of the infundibular septum during embryologic
development

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2
Q

Result of deviation of infundibular septum ??

UW

A

A malaligned ventricular septal defect (VSD) with an overriding aorta

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3
Q

Clinical presentation of FOT ?

UW

A
  1. RV outflow obstruction -systolic murmur
  2. Peripheral systemic vascular resistance - afterload
  3. dec R-L shunting across VSD

UWorld

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4
Q

in FOT right ventricular outflow tract obstruction determine —

uw

A

the degree of right-to-left intracardiac shunting and resulting cyanosis

UW

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4
Q

FOT patients + a tet spell consequence — ??

UWorld

A

=increases systemic vascular resistance and =decreases right-to-left shunting, thereby =increasing pulmonary blood flow =improving oxygenation status

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5
Q

The major defects in tetralogy of Fallot are&raquo_space;????

UW

A

right ventricular outflow tract (RVOT) obstruction and a ventricular septal
defect (VSD)

UW

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6
Q
A
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7
Q
A
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8
Q

Right ventricular tract obstruction association in FOT ??

UW

A

During these episodes right ventricular pressure is increased and
pulmonary arterial and left atrial pressures are decreased as blood is shunted away from the pulmonary circulation
(ie, right-to-left shunting through the VSD)

UWorld

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9
Q

What prevents closure of ductus arteriiosus ??

uW

A

Prostaglandin E1

UW

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10
Q

Severe tetralogy of Fallot is a ductal-dependent lesion that requires blood flow through the ductus arteriosus (from
the aorta to the pulmonary artery) for adequate oxygenation

A

Ductus arteriosus - FOT = PE1

UWOlr=d

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10
Q

In suspected ductal dependent neonate what should be administrated ?

UW

A

Prostaglandin E1
as it open DA

UW

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11
Q

RVOT & VSD in FOT ??

UW

A

These episodes involve decreased blood flow through the RVOT, causing
disappearance of the associated systolic murmur, and reduced oxygen saturation of the left ventricular blood being
pumped into the systemic circulation

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12
Q
A
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13
Q

Polycythemia causes related to FOT ??

UW

A

increased erythropoietin stimulated by conditions causing chronic hypoxemia, such
as cyanotic congenital heart disease (eg, tetralogy of Fallot).

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14
Q

Hypoxemia in these cases is caused by right-to-left
shunting (ie, underperfusion of the pulmonary arteries).

A

THATS ALL