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USMLE-Pathology-(Pathoma+ FA+UWorld) > Congenital Kidney Disease > Flashcards

Congenital Kidney Disease Flashcards

Pathoma-125

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USMLE® Step 1 flashcards
1
Q

Most common congenital renal anomaly ?

A

Horseshoe kidney

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2
Q

In horseshoe kidney location of kidney ?

A

Lower abdomen

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3
Q

Horseshoe kidney what just happened?

A

Conjoined kidneys usually connected at the lower pole

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4
Q

Horseshoe kidney process ?

A

Inf mesenteric artery
Ascent = From Pelvis —- Abdomen
Then= Cought on there

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4
Q

Absent kidney formation ?
Dx ?

A

Renal Agenesis

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5
Q

Renal agenesis type ?

A
  1. Unilateral
  2. Bilateral
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6
Q

Unilateral renal agenesis ?

A
  1. Hypertrophy
  2. Hyperfiltration = Inc risk of Renal F

125

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7
Q

Bilateral Renal ageneis ?

A
  1. Oligohydramnios
  2. Lung hypoplasia
  3. Flat face
  4. Low set ears
  5. Defects in extremities
  6. Potter sequence
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8
Q

Incompatible with life
Dx ?

A

Renal agenesis

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9
Q

Dysplastic kidney disease must be difference from ?

A

PKD
unilateral

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9
Q

Potter sequence in which renal congenital anomely ?

A

Renal agenesis

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10
Q

Dysplastic kidney which part of kidney affected ?

A

Renal parenchyma

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11
Q

Dysplastic kidney manifestation ?

A
  1. Noninherited
  2. Congenital malformation
  3. Cyst
  4. Abnormal tissue
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12
Q

Polycystic kidney Disease which side ?

A

Bilateral

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13
Q

PKD which site of kidney ?

A

Renal cortex & medulla

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14
Q

Young Adult manifestation of PKD ?

A
  1. HTN= inc Renin
  2. Hematuria
  3. Renal F worsening
15
Q

PKD manifestation ?

A

Inherited defect + Enlarged kidney + Cyst

15
Q

Association of PKD ?

A
  1. Congenital hepatic fibrosis
  2. Portal HTN
  3. Hepatic cyst
16
Q

PKD fate in infants ?

A
  1. HTN
  2. Renal Failure
17
Q

PKD newborn fate ?

A

Potter sequence

18
Q

Association of PKD ?

A
  1. Hepatic cyst
  2. Berry aneurysm
  3. Mitral valve prolapse

125

19
Q

Which mutation for cyst formation in PKD ?

A

APKD1
APKD2 gene

20
Q

Medullary cystic kidney diseases?

A

inherited autosomal dominant defect=Medullary collecting ducts

21
Q

Site of congenital anomely confusion ??

A
  1. Dysplastic kidney D=Renal parenchyma
  2. PKD = Renal cortex & medulla
  3. MCKD = Medullary collecting ducts

Inherited autosomal disease

21
Q

MCKD presentation?

A
  1. Parenchymal fibrosis
  2. Shrunken kidney
  3. Worsening Renal F

USMLE-Pathology-(Pathoma+ FA+UWorld) (75 decks)

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