Chronic Gastritis Flashcards
1
Q
Chronic gastritis ?
A
Chronic inflammation in stomach mucosa
2
Q
Chronic Autoimmune G site >?
A
Stomach body & fundus
2
Q
Types of CG ?
A
- Chronic Autoimmune G
- Chronic H pylori G
3
Q
Cause of HPyCG ?
A
H Pylori ureases + Proteases + Inflammantion= Weaken mucosal defense
3
Q
H Pylori G site ?
A
Antrum
4
Q
Cause Autoimmune CG ?
A
AB against parietal cells / Intrinsic factors
5
Q
ACG which hypersensitivity?
A
Type-4
6
Q
Clinical features of Autoimmune CG ?
A
- Atrophy of mucosa
- Intestinal metaplasia
- Achlorhydria
- Inc Gastrin level
- Antral G cell hyperplasia
- dec Intrinsic factor
- Megaloblastic anemia / Perniciuos
7
Q
Which antigen in ACG ?
A
HLA-DR Atg
8
Q
ACG which cancer risk ?
A
Gastric adenocarcinoma
Intestinal type
8
Q
Tx of CG ?
A
Triple therapy
9
Q
Clinical features of HPyCG ?
A
- Epigastric Ab pain
- Peptic ulcer disease
- \Gastric adenocarcinoma’
- Intestinal type G adenocarcinoma
- MALT lymphoma
10
Q
Triple therapy in CG .?
A
- Resolves gastritis / ulcer
- Reverse intestinal metaplasia
- Negative Urea breath test
- Lack of stool antigen
11
Q
Lack of stool antigen ?
A
HPyCG
12
Q
Negative urea breath test ?
A
HPyCG
