Lower Urinary Tract Carcinoma

Question 1

Most common lower urinary tract Ca ?

Answer 1

Urothelial transitional cell carcinoma

Question 2

Risk factors ?

Painless hematuria + Older

Answer 2

1. Smoke
2. Cigarette
3. Napthylamine
4. Azo dyes
5. cyclophosphamide
6. Phenacetin

Question 3

Pathway ?

2

Answer 3

1. Flat - Flat tumor - p53
2. Papillary- not p53

Question 4

Tumor character?

Answer 4

1. Multifocal
2. Recur-Field defect

Question 5

Maliganant proliferation of squamous cell ?

Answer 5

Squamous cell C a

Question 6

SCCa risk factor ?

Answer 6

1. Chronic cystitis
2. Schistosoma heamatobium infection-Egyptian male
3. Long styanding nephrolithiasis

Question 7

Malignant proliferation of gland ?

Answer 7

Adenocarcinoma

Question 8

Causes of adenocarcinoma ?

Answer 8

1. Urachal remnant
   =Tumor developed in the dome of the bladder

2.Cystitis glandularis /Extrophy

Question 9

Exstrophy ? in adenocarcinoma ?

Answer 9

Congenital failure to fotm the caudal portion of the ant abdomial and bladder walls

135 pathoma