Unit 3- Genital and GI Flashcards
Genital and GI pathogens
Campylobacter, Helicobacter, Arcobacter, and Lawsonia
Campylobacter
Gram neg curved rods, motile, non-hemolytic, microaerophilic, oxidase +, urease -, selective media
Microaerophilic
Needs low oxygen %
Pathogenic Campylobacter
C fetus subsp fetus, C fetus subsp venereales, C jejuni, C coli, Lawsonia intracellularis, C upsaliensis
Campylobacter fetus subsp venereales
Venereal transmission, old bulls permanent carriers, placental and fetal infection
C fetus subsp venerealis Pathogenesis
Bacteria colonize female reproductive in ascending infection
Bovine Genital Campylobacteriosis
C fetus subsp venerealis infection, endometritis, reduced conception rate = repeat breeders
C fetus subsp Venerealis Virulence
Proteinaceous micro capsule S layer, serum resistance, antigenic phase variation
C fetus subsp venerealis Diagnosis
Microaerophilic culture, fluorescent antibody test, PCR
C fetus Immunity
S layer changes to elude antibodies, vaccination not reliable
C fetus subsp fetus Disease
Rare disease in cattle causing abortion, abortion in sheep, genital I nfection after bacteremia
C fetus subsp fetus
S layer important antigens, inhabits GI, transmitted by ingestion
C fetus subsp fetus Lesions
Mid to late term abortion, focal hepatic necrosis, mixed infection with Chlamydia, fibrinous arteritis in fetus, bloody fetal fluid
C fetus subsp fetus Immunity
Vaccination based on LPS, S layer antigens, intestinal and systemic antibodies important
C fetus subsp fetus Diagnosis
Lesions, selective media, PCR, fluorescent antibody staining of cotyledon impression smears