Unit 3- Genital and GI Flashcards
Genital and GI pathogens
Campylobacter, Helicobacter, Arcobacter, and Lawsonia
Campylobacter
Gram neg curved rods, motile, non-hemolytic, microaerophilic, oxidase +, urease -, selective media
Microaerophilic
Needs low oxygen %
Pathogenic Campylobacter
C fetus subsp fetus, C fetus subsp venereales, C jejuni, C coli, Lawsonia intracellularis, C upsaliensis
Campylobacter fetus subsp venereales
Venereal transmission, old bulls permanent carriers, placental and fetal infection
C fetus subsp venerealis Pathogenesis
Bacteria colonize female reproductive in ascending infection
Bovine Genital Campylobacteriosis
C fetus subsp venerealis infection, endometritis, reduced conception rate = repeat breeders
C fetus subsp Venerealis Virulence
Proteinaceous micro capsule S layer, serum resistance, antigenic phase variation
C fetus subsp venerealis Diagnosis
Microaerophilic culture, fluorescent antibody test, PCR
C fetus Immunity
S layer changes to elude antibodies, vaccination not reliable
C fetus subsp fetus Disease
Rare disease in cattle causing abortion, abortion in sheep, genital I nfection after bacteremia
C fetus subsp fetus
S layer important antigens, inhabits GI, transmitted by ingestion
C fetus subsp fetus Lesions
Mid to late term abortion, focal hepatic necrosis, mixed infection with Chlamydia, fibrinous arteritis in fetus, bloody fetal fluid
C fetus subsp fetus Immunity
Vaccination based on LPS, S layer antigens, intestinal and systemic antibodies important
C fetus subsp fetus Diagnosis
Lesions, selective media, PCR, fluorescent antibody staining of cotyledon impression smears
Intestinal Campylobacter
C jejuni, coli, and lari
Intestinal Campylobacter Disease
Oral transmission, enteritis, bovine mastitis, sheep abortion, hepatitis in chicken
Intestinal Campylobacter Virulence Factors
LOS, enterotoxin, cytotoxins
Intestinal Campylobacter Pathogenesis
Bacteria penetrate mucosa and infect enterocytes, motility allows to reach deeper tissues and phagocytes
Campylobacter Selective Agar
Blood agar, charcoal selective agar
Campylobacter jejuni Diagnosis
Fever, abdominal pain, nausea, bloody feces, Skirrows selective medium, microaerophilic, PCR
Campylobacter upsaliensis
Common in pets, cytolethal distending toxin
Campylobacter hyointestinalis and mucosalis
Proliferative enteritis and intestinal adenomatosis in pigs
Campylobacter Public Health
Fetus, jejuni, and coli present in many animals, highly infectious and oral transmission, enteritis and systemic infection in human
Campylobacter Control
Antimicrobials rarely used for farm animal, supportive care, artificial insemination, removal of abortion, hygiene, cull carriers, bacterin vaccines
Helicobacter causing gastritis in cats
Helicobacter felis, canis, pylori, and heilmanii
Helicobacter causing gastritis in dogs
Helicobacter bilis, felis, canis, salomonis, rappini, heilmanii
Helicobacter Gastritis Clinical Signs
Vomiting, abdominal pain, fever, diarrhea, weight loss, malaise
Helicobacter causing hepatitis
Helicobacter hepaticus and bilis, hepaticus leads to hepatic neoplasia
Helicobacter suis
Gastritis in pigs
Arcobacter
Aerotolerant, associated with abortion and mastitis, darting motility, growth in ambient air on Yersinia agar
Lawsonia intracellularis
Obligate intracellular in epithelial cells, proliferative intestinal enteropathy, chronic diarrhea
Wet Tail Disease
Intestinal enteropathy in pig and hamster caused by Lawsonia intracellularis
Lawsonia Disease
Acute hemorrhagic enteropathy and diarrhea, chronic mild diarrhea and reduced growth, loss of villous structure
Lawsonia Diagnosis
Pathology, histopathology, fluorescent antibody, PCR
