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Bacteriology > Unit 3- Chlamydia > Flashcards

Unit 3- Chlamydia Flashcards

1
Q

Reasons for Intracellularity

A

Protection from permeable cell membrane, ATP shortage, cholesterol demand

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2
Q

Chlamydia and Coxiella Lifecycle

A

Spore like particle extracellularly, actively replicates inside host cells

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3
Q

Chalmydia Intracellular

A

Reticulate inclusion bodies

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4
Q

Coxiella Intracellular

A

Large cell variant

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5
Q

Anaplasma and Ehrlichia Intracellular

A

Reticulate cells (morula)

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6
Q

Chlamydia Extracellular

A

Elementary body

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7
Q

Coxiella Extracellular

A

Small cell variant

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8
Q

Anaplasma and Ehrlichia Extracellular

A

Dense cored cells

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9
Q

Rickettsia Intracellular

A

Freely moves in cytoplasm without hiding in vacuoles

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10
Q

Anaplasma Transmission

A

Ticks

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11
Q

Ehrlichia Transmission

A

Ticks

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12
Q

Rickettsia Transmission

A

Ticks, lice, mites, fleas

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13
Q

Coxiella Transmission

A

Airborne

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14
Q

Chlamydia Transmission

A

Airborne, sex, elementary body contagious transmission

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15
Q

Mycoplasma Transmission

A

Airborne

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16
Q

MAKePSR Syndrome

A

Mastitis, arthritis, keratoconjunctivitism, pneumonia, septicemia, reproductive disorder caused by chlamydia and mycoplasma tropism for mucous membranes

17
Q

Rickettsiales Predilection Sites

A

RBC, WBC, or blood vessels

18
Q

Iceberg Concept

A

Presence of clinical cases indicates huge members have subclinical infection, multiple species may be involved

19
Q

Chlamydia

A

Gram neg cocci, little peptidoglycan, giemsa stain best, obligate intracellular

20
Q

Why is Chlamydia obligate intracellular?

A

Cytoplasmic membrane highly permeable, cannot produce amino acids and ATP

21
Q

Chlamydia Elementary Body

A

Extracellular form, environmentally resistant, airborne, infects vertebrates

22
Q

Chlamydia Aberrant Body

A

Characterizes persistent infection, formed during stressful conditions from antimicrobials or host immune

23
Q

Chlamydia Hosts

A

Some interspecies transmission, wide variety of hosts

24
Q

Chlamydia Pathogenesis

A

Attacks columnar epithelium of epithelial cells and mucous membranes

25
Q

Chlamydiosis

A

MaKePSRRD syndrom

26
Q

Chlamydia abortus

A

Ovine abortion storms and placentitis, follicular vaginitis in cow

27
Q

Chlamydia Virulence Factors

A

Neuraminidase, catalase, protease, LPS, T3SS, intracellular survival

28
Q

Gold Standard Test for Chlamydia

A

Indirect immunofluorescent IgG antibody assay

29
Q

Chlamydia Culture

A

Requires living cell lines, chicken embryo, buffalo green monkey kidney cells

30
Q

Chlamydia Treatment

A

Antibiotics early in infection, induces aberrant bodies in persistent chlamydial infection

31
Q

Chlamydia abortus Vaccine

A

Prevents abortion in small ruminant

32
Q

Chlamydia felis Vaccine

A

Prevents keratoconjunctivitis in pets

33
Q

Chlamydia Groups

A

Avian, Mammalian, Human

Bacteriology (44 decks)

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