Unit 2- Proteus

Question 1

Proteus

Answer 1

Lactose non fermenter, H2S gas producer, urease positive, ammonia smell, highly motile, swarming

Question 2

Dienes Lines

Answer 2

Differentiate identical and different strains by boundaries formed

Question 3

Swarming Motility

Answer 3

Formation of multi-cellular rafts of elongated, hyperflagellated swarmer cells that can move over solid surfaces

Question 4

Serotypes

Answer 4

Multiple O antigens

Question 5

Hosts

Answer 5

All vertebrates

Question 6

Habitat

Answer 6

GI, vulva, skin, oral mucosa, polluted water and soil in environment

Question 7

Surface Structures

Answer 7

Fimbriae, flagella, LPS endotoxin, O polysaccharides, biofilm, internalization into host cells

Question 8

Enzymes

Answer 8

Urease causes urine pH elevation and kidney stones, proteases, deaminases

Question 9

Toxins

Answer 9

Hemolysins, proteus toxic agglutinin, zinc and phosphate transport systems, siderophores

Question 10

Potent Virulent Factors

Answer 10

Flagella elongation and urease production

Question 11

Urease

Answer 11

Converts urea in urine to ammonia, changing pH and causing kidney stone

Question 12

P mirabilis Stones

Answer 12

Struvite renal stones and UTI

Question 13

P penneri Stones

Answer 13

Nosocomial UTI and sepsis

Question 14

P vulgaris

Answer 14

Nosocomial UTI and sepsis

Question 15

Ascending UTI

Answer 15

Urease, swarming motility, hemolysin, other virulence factors

Question 16

Proteus mirabilis

Answer 16

Ulceration in GI, septicemia, suppurative necrotic lesions, septic thrombi and infarction in kidney, nephritis, pyelonephritis, struvite renal stones