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Bacteriology > Unit 2- Actinobacillus > Flashcards

Unit 2- Actinobacillus Flashcards

1
Q

Actinobacillus

A

Gram negative coccobacillus, filamentous, fermentative without gas, some grow on macconkey, sticky colonies, beta hemolysis, obligate mucosal parasites

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2
Q

Actinobacillus pleuropneumoniae

A

Pig specific, biovar 1 requires V factor from chocolate agar, hemolytic

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3
Q

V Factor

A

NAD

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4
Q

Swine Pleropneumonia

A

A pleropneumoniae, fibrinous pleuritis and pneumonia, hemorrhagic necrotic lesions, minor lesions, chronic infection carries disease to nonimmune herds

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5
Q

Swine Pleuropneumoniae Clincal Signs

A

Trembling, anorexia, fever, dyspnea, hemorrhage, chonic carrier

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6
Q

A pleuropneumoniae Virulence

A

Capsule, LPS, RTX toxins, adhesins

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7
Q

RTX Toxins

A

Cause hemorrhagic and necrotic lesions by lysing red and white blood cells

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8
Q

A pleuropneumoniae Compomising Factors

A

Some serotypes highly virulent, stress and overcrowding

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9
Q

A pleuropneumoniae Immunity

A

Neutralizing antibodies to RTX, other antibodies enhance opsonization and clearance

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10
Q

A pleuropneumoniae Vaccines

A

Live attenuated to induce neutralizing antibodies

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11
Q

Actinobacillus equuli subsp equuli

A

Tonsils, intestine, and respiratory tract of horse and pig, can rarely infect other species, grows on macconkey, nonhemolytic, RTX toxin

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12
Q

Sleepy Foal Disease

A

A equuli subsp equuli causes acute bacteremia, can lead to aneurism if coinfected with strongylus vulgaris

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13
Q

Actinobacillus equuli subsp haemolyticus

A

Infects horse respiratory, less common, hemolytic, RTX toxin

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14
Q

A equuli subsp haemolyticus Disease

A

Adult abortion, metritis, mastitis, meningitis, respiratory disease, wound infection, adn endocarditis, sometimes sleepy foal disease

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15
Q

A equuli Virulence

A

LPS, adherence factors, weak RTX tocin

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16
Q

A equuli Compromising Factors

A

Mares carrying prior to delivery, stress, parasitism

17
Q

A equuli Immunity

A

Sanitation to birthing environment, maternal colostrum, prebreeding culture screening

18
Q

Actiobacullus lignieresii

A

Cattle and sheep but zoonotic, oral commensal, requires serum or blood and CO2 for isolation

19
Q

Wooden Tongue

A

A lignieresii causes tumor like lesions of tongue and oral cavity that ulcerate following trauma, may cause granules

20
Q

A lignieresii Virulence

A

LPS, weak RTX toxin, dissemination, resistance to host defenses

21
Q

A lignieresii Compromising Factors

A

Normal flora, self innoculation of buccal epithelium following trauma

22
Q

A lignieresii Immunity

A

Cellular Th1 immunity, granulomatous reaction common

23
Q

A lignieresii Treatment

A

Sodium/potassium iodide on local lesions

24
Q

Actinobacillus suis

A

Swine mucosal surfaces, sticky on MacConkey, hemolytic

25
Q

A suis Disease

A

Bacteremia in piglets, endocarditis, pericarditis, edema, petechiae, fever, respiratory distress, localized lesions in adults

26
Q

A suis Virulence

A

RTX toxin, capsule, LPS, adhesions

27
Q

A suis Transmission

A

Carried in respiratory tract and tonsils, transmission at young age

28
Q

A suis Treatment

A

Confirm AMR with susceptibility test

29
Q

Diagnosis

A

Pure culture

30
Q

A pleuropneumoniae Diagnosis

A

Requires V factor for growth, chocolate or blood and staph streak agar required

31
Q

A lignieresii Diagnosis

A

Requires blood and CO2, granules present

32
Q

A equuli Diagnosis

A

MacConkey

Bacteriology (44 decks)

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