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2 - CPR (cardio) > Systemic Vasculitides - medium/large vessels > Flashcards

Systemic Vasculitides - medium/large vessels Flashcards

1
Q

What are 3 Systemic Vasculitides that affect MEDIUM sized blood vessels?

A
  1. Thromboangiitis Obliterans
  2. Polyarteritis Nodosa
  3. Kawasaki Disease
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2
Q

What are 3 Systemic Vasculitides that affect MEDIUM sized blood vessels?

A
  1. Thromboangiitis Obliterans
  2. Polyarteritis Nodosa
  3. Kawasaki Disease
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3
Q

Who is affected by Thromboangiitis Obliterans?

A

Young males who SMOKE – must smoke

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4
Q

Symptoms of Thromboangiitis Obliterans?

A

Thrombosis of distal vessels

= loss of digits, hands, feet

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5
Q

What will be seen on angiography with Thromboangiitis Obliterans?

A

Corkscrew appearance

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6
Q

Treatment for Thromboangiitis Obliterans?

A

Stop smoking

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7
Q

What is Polyarteritis Nodosa associated with?

A

Hepatitis B Virus

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8
Q

Signs of Polyarteritis Nodosa?

A

Livedo Reticularis, ulcers and gangrene

Neuropathy – foot drop

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9
Q

Signs of Polyarteritis Nodosa?

A

Livedo Reticularis, ulcers and gangrene

Neuropathy – foot drop

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10
Q

What is newly acquired with Polyarteritis Nodosa?

A

HTN

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11
Q

Lung findings with Polyarteritis Nodosa?

A

SPARED – NO lung findings

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12
Q

What will be seen on biopsy of Polyarteritis Nodosa?

A

Fibrinoid Necrosis

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13
Q

What will be seen on angiography with Polyarteritis Nodosa?

A

Micro-aneurysm

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14
Q

Who is affected by Kawasaki Disease?

A

Japanese males less than 5 years old

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15
Q

Who is affected by Kawasaki Disease?

A

Japanese males less than 5 years old

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16
Q

Symptoms of Kawasaki Disease?

A

Fever, LAD, rash and strawberry tongue

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17
Q

Symptoms of Kawasaki Disease?

A

Fever, LAD, rash and strawberry tongue

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18
Q

What is the usually cause of morbidity with Kawasaki Disease?

A

Coronary A. Involvement

19
Q

Treatment for Kawasaki Disease?

A

IVIG and Aspirin

20
Q

What are 2 Systemic Vasculitides that affect LARGE blood vessels?

A
  1. Takayasu Arteritis

2. Giant Cell Arteritis

21
Q

What are 2 Systemic Vasculitides that affect LARGE blood vessels?

A
  1. Takayasu Arteritis

2. Giant Cell Arteritis

22
Q

Takayasu Arteritis affects which large vessels?

A

Aorta and renal arteries

23
Q

Takayasu Arteritis affects the Aorta and obliterates?

A

Peripheral pulses = “pulseless disease”

24
Q

Possible aorta complications with Takayasu Arteritis?

A

Dilation, rupture, aneurysm

25
Q

When Takayasu Arteritis affects the renal arteries, what will it cause?

A

HTN

Retinopathy with copper wiring

26
Q

When Takayasu Arteritis affects the renal arteries, what will it cause?

A

HTN

Retinopathy with copper wiring

27
Q

What does Angiography show with Takayasu Arteritis?

A

Long smoother tapered stenosis

28
Q

Histo findings with Takayasu Arteritis?

A

Granuloma with some giant cells

29
Q

What vessels are affected by Giant Cell Arteritis?

A

Cranial arteries and aortic arch

30
Q

Symptoms of Giant Cell Arteritis?

A

Headache
Jaw Claudication = pain while chewing
Vision abnormalities

31
Q

Symptoms of Giant Cell Arteritis?

A

Headaches
Jaw Claudication = pain while chewing
Vision abnormalities

32
Q

What HLA is associated with Giant Cell Arteritis?

A

HLA-DR4

33
Q

What will be very elevated with Giant Cell Arteritis?

A

ESR

34
Q

What is needed to diagnose Giant Cell Arteritis and what will it show?

A

Temporal A. biopsy = Multinucleated giant cells

35
Q

What is needed to diagnose Giant Cell Arteritis and what will it show?

A

Temporal A. biopsy = multinucleated giant cells

36
Q

You should administer glucocorticoids ____ biopsy with Giant Cell Arteritis

A

BEFORE

37
Q

What will result in the patient if you do not treat them with Giant Cell Arteritis?

A

Blindness

38
Q

What frequently coexists with Giant Cell Arteritis?

A

Polymyalgia Rheumatica

39
Q

What frequently coexists with Polymyalgia Rheumatica?

A

Giant Cell Arteritis

40
Q

Polymyalgia Rheumatica

A

Subjective feelings of weakness due to muscle pain with no true objective weakness

41
Q

Polymyalgia Rheumatica

A

Subjective feeling of weakness due to muscle pain with no true objective weakness

42
Q

Stiffness, soreness and muscle pain that causes subjective feeling of weakness

A

Polymyalgia Rheumatica

43
Q

What is elevated with Polymyalgia Rheumatica?

A

ESR and CRP

44
Q

What frequently coexists with Giant Cell Arteritis?

A

Polymyalgia Rheumatica

= subjective weakness due to muscle pain with no true objective wekaness

2 - CPR (cardio) (44 decks)

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