HTN Drugs Cont. Flashcards
Hypertension can be primary or secondary. What are some common causes of secondary HTN?
Renal disease, pheochromocytoma, obstructive sleep apnea, alcohol/drug induced, primary aldosteronism
What can cause Renovascular HTN?
secondary HTN
Renal A. stenosis (bilateral or unilateral)
What 3 signs may suggest bilateral Renovascular HTN over primary HTN?
Flash pulmonary edema
Progressive renal failure
Refractory CHF
What 3 signs may suggest bilateral Renovascular HTN over primary HTN?
Flash pulmonary edema
Progressive renal failure
Refractory CHF
What Calcium Channel Blockers (2) can be used for Hypertensive emergencies?
Nicardipine
Clevidipine
What Vasodilators (3) can be used for Hypertensive emergencies?
Hydralazine
Nitroglycerin
Nitroprusside
Giving Hydralazine for a Hypertensive emergency is _____
Unpredictable
Giving Nitroprusside for a Hypertensive emergency, what should you monitor and what toxicity is possible?
- Monitor intra-arterial BP
- - cyanide toxicity is possible
What beta1 blocker can be given for a Hypertensive emergency?
Esmolol
What alpha1 and beta blocker can be given for a Hypertensive emergency?
Labetalol
Labetalol is an alpha1 and beta blocker. What is it useful for in situations of hypertensive emergencies?
Hyperadrenergic syndromes
What is an alpha and beta blocker given in Hypertensive emergencies?
Phentolamine
Phentolamine is an alpha and beta blocker. What is it useful for in situations of hypertensive emergencies?
Excessive catecholamines
What is a Dopamine Agonist used in Hypertensive emergencies?
Fenoldopam
What is an ACEi used in Hypertensive emergencies?
Enalaprilat
Enalaprilat is an ACEi. What is it useful with in situations of hypertensive emergencies?
Useful when there is increased renin activity
Goal of Aortic Dissection treatment?
Anti-impulse therapy = BP <120 and HR<60
What are the 2 drugs that are the best options for Aortic Dissection treatment?
Esmolol
Labetalol
What are the 2 drugs that are the best options for Aortic Dissection treatment?
Esmolol
Labetalol
What are 2 alternatives to Esmolol/Labetalol when treating Aortic Dissections?
Verapamil
Diltiazem
What are 2 alternatives to Esmolol/Labetalol when treating Aortic Dissections?
Verapamil
Diltiazem
If the BP is still > 120 with an Aortic Dissection after Anti-impulse therapy, what should you add and what an example?
Add a vasodilator
- Nitroprusside
If the BP is still >120 with an Aortic Dissection after giving Anti-impulse therapy, what should you add and what is an example and its alternative?
Vasodilator = Nitroprusside
– Alternative - Nicardipine
