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2 - CPR (cardio) > Primary HTN Drugs > Flashcards

Primary HTN Drugs Flashcards

1
Q

What are the 4 drug classes that are primary agents for HTN?

A

ACEi
ARB
Thiazide Diuretics
Calcium Channel Blockers (CCB)

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2
Q

What are the 4 drug classes that are primary agents for HTN?

A

ACEi
ARB
Thiazide Diuretics
Calcium Channel Blockers (CCB)

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3
Q

What are the 4 ACEi?

A

Captopril
Lisinopril
Benazepril
Enalapril

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4
Q

What are the 3 ARBs?

A

Losartan
Valsartan
Candesartan

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5
Q

What are the 3 Thiazide Diuretics?

A

HCTZ
Chlorthalidone
Metolazone

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6
Q

What are the 2 types of Calcium Channel Blockers (CCB)?

A

Dihydropyridines

NON-dihydropyridines

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7
Q

What are the Dihydropyridine CCBs?

A

Nifedipine
Amlodipine
Felodipine

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8
Q

What are the Dihydropyridine CCBs?

A

Nifedipine
Amlodipine
Felodipine

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9
Q

What are the Non-dihydropyridine CCBs?

A

Verapamil

Diltiazem

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10
Q

What are the Non-dihydropyridine CCBs?

A

Verapamil

Diltiazem

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11
Q

Where do Thiazide Diuretics target?

A

Distal convoluted tubule

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12
Q

MOA for Thiazides and are they K+ sparing/losing?

A

(-) NaCl cotransporter

- K+ losing

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13
Q

Thiazide diuretics are NOT effective in patients with?

A

LOW GFR

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14
Q

What electrolyte changes/possible allergy do Thiazide diuretics cause?

A

Hypo-electrolytes (HYPERcalcemia)

- Sulfonamide allergy patients should not take

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15
Q

MOA for ACEi?

A

(-) ACE from converting Angiotensin 1 to Angiotensin 2

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16
Q

What is the half life for Captopril (ACEi)?

A

1.7 hours

17
Q

Which ACEis have longer half lives than Captopril (1.7 hrs)?

A

Lisinopril

Benazepril

18
Q

What are the possible toxicities seen with ACEi?

A

Angioedema, cough, fetal toxicity in 2/3rd trimesters especially

19
Q

MOA for ARBs?

A

Block Angiotensin 2 receptors

20
Q

What are the primary classes and agents for treating HTN?

A
  • ACEi - captopril, lisinopril, benazepril, enalapril
  • ARB - losartan, valsartan, candesartan
  • Thiazide diuretics - HTCZ, chlorthalidone, metolazone
  • Calcium Channel Blockers
    • Dihydropyridines (amlodipine, felodipine, nifedipine)
    • Non-dihydropyridines (verapamil, diltiazem)

2 - CPR (cardio) (44 decks)

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