Connective Tissue Disorders - Scleroderma/Sjogren Flashcards
What are the 3 types of Scleroderma?
- Localized
- Limited (CREST)
- Diffuse
What are the 3 types of Scleroderma?
- Localized
- Limited (CREST)
- Diffuse
What is the hallmark of Scleroderma?
Thickening and hardening of skin
What is the hallmark of Scleroderma?
Thickening and hardening of skin
Are there approved therapies for Scleroderma?
NO - treat symptoms
What do most patients have with Scleroderma?
Secondary Raynaud’s Phenomenon
Localized Scleroderma - skin and internal organ involvement?
Patches of thickened and hardened skin
- NO organ involvement
Discreet areas of discolored skin induration
(morphea = patches) is seen with?
Localized Scleroderma
Is Raynaud’s phenomenon present with Localized Scleroderma?
NO
Symptoms of Localized Scleroderma?
Usually Asymptomatic or itching/pain of localized areas of discolored skin induration patches (morphea)
A biopsy of the skin with Localized Scleroderma looks the same as?
Other forms of Scleroderma
Limited Scleroderma - skin and organ involvement?
Thickening and hardening of skin of fingers/toes, face/neck and distal extremities
- SOME organ involvement
Limited Scleroderma CREST symptoms?
CREST
- Calcinosis Cutis
- Raynaud’s Phenomenon
- Esophageal Dysmotility
- Sclerodactyly
- Telangiectasia
- progressive pulmonary A. HTN = dyspnea
Limited Scleroderma CREST symptoms?
CREST
- Calcinosis Cutis
- Raynaud’s Phenomenon
- Esophageal Dysmotility
- Sclerodactyly
- Telangiectasia
- Pulmonary A. HTN = Dyspnea
What pulmonary change is seen with Limited Scleroderma?
Pulmonary A. HTN = Dyspnea