Drugs to treat Shock Flashcards
If a patient is Hypotensive, what should you give them? And what is the one time you should NOT give them that?
Crystalloid (IV saline) - 30 mL/kg
– Do NOT give if they are in Cardiogenic Shock
If a patient is Hypotensive, what should you give them? And what is the one time you should NOT give them that?
Crystalloid (IV saline) - 30mL/kg
– Do NOT give if they are in Cardiogenic Shock
Crystalloid increases the cardiac filling pressure, what is the goal for the JVP?
10-12
Epinephrine MOA
(+) alpha and beta receptors
= vasoconstriction, elevates contractility and broncodilates
If a patient presents with Anaphylactic Shock, what should be given immediately?
Epinephrine via IM
If a patient presents with Anaphylactic shock, what should be given immediately and what may or may not be added?
Epinephrine
- +/- Antihistamine
- +/- Inhaled Albuterol
Hypovolemic Shock due to Blood loss < 15% treatment?
Crystalloid
Hypovolemic Shock due to blood loss of 15-30% treatment?
Crystalloid
Hypovolemic Shock due to blood loss of 30-40% and the patient is anxious/confused, what is the treatment?
Crystalloid +/- blood
Hypovolemic Shock due to > 40% blood loss where the patient is confused/lethargic treatment?
Crystalloid + Blood!
Are drugs generally required when treating hypovolemic shock due to blood loss?
No
List Vasopressors/Inotropes available to treat shock
Dopamine Norepinephrine Epinephrine Phenylephrine Dobutamine Vasopressin
Dopamine MOA?
(+) beta receptors are low doses and then (+) alpha receptors are high doses
Norepinephrine MOA?
(+) alpha and beta 1 receptors
Epinephrine MOA?
(+) alpha and beta receptors
Dobutamine MOA?
(+) beta 1 receptors to increase HR and contractility with vasodilation in the periphery
Phenylephrine MOA?
(+) alpha receptors ONLY to elevate BP and decrease HR/contractility
Where does Vasopressin come from?
Posterior pituitary hormone
What receptors does Vasopressin (+) and what is the result?
V1 = Vasoconstriction V2 = Anti-diuretic in kidney
When treating Cardiogenic Shock, what is the best drug?
Norepinephrine
When treating Cardiogenic Shock, what is the best drug to use and what is it better than and why?
Norepinephrine
– Better than Dopamine because Dopamine causes arrhythmias and does not preserve renal function
When treating Cardiogenic Shock, what can be used when the cardiac output is low despite adequate filling pressure?
Dobutamine
With Septic Shock, prompt administration of ____ should be given
Broad-based Antibiotics
What is the 1st line of choice when treating Septic Shock?
Norepinephrine
