Drugs to treat Shock Flashcards

1
Q

If a patient is Hypotensive, what should you give them? And what is the one time you should NOT give them that?

A

Crystalloid (IV saline) - 30 mL/kg

– Do NOT give if they are in Cardiogenic Shock

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2
Q

If a patient is Hypotensive, what should you give them? And what is the one time you should NOT give them that?

A

Crystalloid (IV saline) - 30mL/kg

– Do NOT give if they are in Cardiogenic Shock

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3
Q

Crystalloid increases the cardiac filling pressure, what is the goal for the JVP?

A

10-12

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4
Q

Epinephrine MOA

A

(+) alpha and beta receptors

= vasoconstriction, elevates contractility and broncodilates

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5
Q

If a patient presents with Anaphylactic Shock, what should be given immediately?

A

Epinephrine via IM

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6
Q

If a patient presents with Anaphylactic shock, what should be given immediately and what may or may not be added?

A

Epinephrine

  • +/- Antihistamine
  • +/- Inhaled Albuterol
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7
Q

Hypovolemic Shock due to Blood loss < 15% treatment?

A

Crystalloid

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8
Q

Hypovolemic Shock due to blood loss of 15-30% treatment?

A

Crystalloid

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9
Q

Hypovolemic Shock due to blood loss of 30-40% and the patient is anxious/confused, what is the treatment?

A

Crystalloid +/- blood

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10
Q

Hypovolemic Shock due to > 40% blood loss where the patient is confused/lethargic treatment?

A

Crystalloid + Blood!

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11
Q

Are drugs generally required when treating hypovolemic shock due to blood loss?

A

No

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12
Q

List Vasopressors/Inotropes available to treat shock

A
Dopamine
Norepinephrine
Epinephrine
Phenylephrine
Dobutamine
Vasopressin
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13
Q

Dopamine MOA?

A

(+) beta receptors are low doses and then (+) alpha receptors are high doses

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14
Q

Norepinephrine MOA?

A

(+) alpha and beta 1 receptors

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15
Q

Epinephrine MOA?

A

(+) alpha and beta receptors

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16
Q

Dobutamine MOA?

A

(+) beta 1 receptors to increase HR and contractility with vasodilation in the periphery

17
Q

Phenylephrine MOA?

A

(+) alpha receptors ONLY to elevate BP and decrease HR/contractility

18
Q

Where does Vasopressin come from?

A

Posterior pituitary hormone

19
Q

What receptors does Vasopressin (+) and what is the result?

A
V1 = Vasoconstriction
V2 = Anti-diuretic in kidney
20
Q

When treating Cardiogenic Shock, what is the best drug?

A

Norepinephrine

21
Q

When treating Cardiogenic Shock, what is the best drug to use and what is it better than and why?

A

Norepinephrine

– Better than Dopamine because Dopamine causes arrhythmias and does not preserve renal function

22
Q

When treating Cardiogenic Shock, what can be used when the cardiac output is low despite adequate filling pressure?

A

Dobutamine

23
Q

With Septic Shock, prompt administration of ____ should be given

A

Broad-based Antibiotics

24
Q

What is the 1st line of choice when treating Septic Shock?

A

Norepinephrine

25
Q

What can be added or substituted for Norepinephrine when treating Septic Shock?

A

Epinephrine

26
Q

What else besides Epinephrine can be added to Norepinephrine when treating Septic Shock?

A

Vasopressin

27
Q

What is the 1st line of choice when treating Septic Shock?

A

Norepinephrine

28
Q

When treating Septic Shock, if there is bradycardia, what can be substituted for the Norepinephrine?

A

Dopamine

29
Q

When is Phenylephrine recommended for Septic Shock?

A

When Norepinephrine is causing arrhythmias

30
Q

At low doses, what can improve septic SHOCK reversal?

A

Corticosteroids

31
Q

At low doses, what can improve septic SHOCK reversal?

A

Corticosteroids

32
Q

For Obstructive Shock, the treatment is dependent on?

A

The cause

33
Q

Tension pneumothorax causing Obstructive Shock treatment?

A

Needle decompression and chest tube placement

34
Q

Cardiac tamponade causing Obstructive Shock treatment?

A

Pericardiocentesis

35
Q

Pulmonary Embolism causing Obstructive Shock treatment?

A

Anticoagulants

36
Q

What can treat acute and recurrent Pericarditis?

A

NSAIDs and Colchicine

- NSAIDs: ibuprofen, aspirin, naproxen

37
Q

MOA for Colchicine?

A

(-) Microtubule formation and white cell migration

38
Q

What can treat acute and recurrent pericarditis?

A

NSAIDs and Colchicine

- NSAIDs: aspirin, naproxen, ibuprofen

39
Q

If the first line of treatment combo for pericarditis does not work, what can you try?

A

Corticosteroids