Direct Adrenomimetics Flashcards
What are 2 Alpha Agonists?
Phenylephrine
Clonidine
What are 2 Alpha Agonists and their preferred receptor type?
Phenylephrine - Alpha 1
Clonidine - Alpha 2
What are 2 Mixed Alpha and Beta Agonists?
Norepinephrine
Epinephrine
What are 2 Mixed Alpha and Beta Agonists and which one does NOT work on Beta 2 receptor types?
Norepinephrine = LACKS beta 2 effects
Epinephrine
What are 3 Beta Agonists?
Dobutamine
Isoproterenol
Albuterol
What are 3 Beta Agonists and their preferred receptor type?
Dobutamine - Beta 1
Isoproterenol
Albuterol - Beta 2
Major effects of Epinephrine?
- Increases HR, force of contraction and conduction velocity at AV node
- Increases systolic BP
- Relaxes Bronchial muscle
- Elevates blood glucose levels
== Alpha and Beta receptor actions!
Major effects of Epinephrine?
- Increases HR, force of contraction and conduction velocity at AV node
- Increases systolic BP
- Relaxes Bronchial muscle
- Elevates blood glucose levels
== Alpha and Beta receptor actions!
Norepinephrine does NOT work on which receptor type?
Beta 2
Major effects of Norepinephrine?
- Reduces heart rate and is a vasoconstrictor
- Increases BP
What receptor does Phenylephrine stimulate and what are the effects?
Alpha 1
= Vasoconstriction with BP elevation
= Decreases HR
What receptor does Clonidine stimulate and what are the effects?
Alpha 2
= Reduction in SNS tone, BP and HR
– (-) NE release at presynaptic neuron
Isoproterenol is a ____ Agonist and what are the major effects?
Beta Agonist
= Increases cardiac output and bronchodilation
= Vasodilator and decreases arterial pressure
What receptor does Dobutamine stimulate and what are the effects?
Beta 1
= Increases heart rate and contraction force
What receptor does Albuterol stimulate and what are the effects?
Beta 2
= Bronchodilation
