PHAR232 - Principles of General Anaesthesia & Euthanising agents Flashcards
1
Q
What are the 3 components of anaesthesia?
A
Analgesia
Loss of consciousness with amnesia
Muscle relaxation
2
Q
What are 3 key proteins associated with inhaled gases?
A
GABA-A channel receptors
- 2 pore domain K+ channels
- NMDA glutamate channel receptors
3
Q
Inhaled anaesthetics and GABA-A
A
GABA receptor channel
4
Q
Binding of inhaled agents to GABA-A receptor channels
A
Protein theory
5
Q
NMDA glutamate receptor
A
MUST KNOW
GABA-A - MUTATION OF AA
2 PORE DOMAIN K+
NMDA RECEPT CHANNELS
ALL OF THESE NEED TO KNOW THE MUTATION OF THE AA FOR GASEOUS INTERACTION
6
Q
MAC equation for 50%
A
MAC value considerations
7
Q
Brain vs body for anaesthetics
A
Mac value further considerations
8
Q
A
Key things to remember
9
Q
Uptake & distribution of General Anaesthetics
A
10
Q
A
