A walk through the brain - week 3 Flashcards

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1
Q

What is a nerve?

A

A nerve consists of a membrane sheath encasing bundles of axons.

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2
Q

Where are the nerves in the brain?

A

Cranial nerves

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3
Q

What do nerves do?

A

Nerves are bundles of fibers that transmit electrical impulses from the central nervous system to the body and back.

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4
Q

What are the 4 structures of a neuron?

A

Cell body (soma)
Dendrites
Axon
Terminals

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5
Q

What is the soma (cell body)?

A

The neuronal cytosol
Contains nucleus
contains cellular organelles

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6
Q

What do dendrites do?

A

Receive messages from another neuron’s terminal buttons

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6
Q

What do dendrites do?

A

Receive messages from another neuron’s terminal buttons

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7
Q

What is an axon ?

A

Slender tube - covered by a myelin sheath

Carries messages (electric charges) from the soma to terminal buttons

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8
Q

What are terminals or (terminal buttons)

A

Small knowbs end of terminals which release neurotransmitters

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9
Q

Where do neurons communicate with each other?

A

The Synapse

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10
Q

What is the ave. length of a neuron?

A

< 1.0mm

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11
Q

How long is the sciatic nerve on ave?

A

1meter

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12
Q

What are nodes of ranvier?

A

Unmyelinated gaps on the axon

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13
Q

In the CNS myelination is made from what cells?

A

Oligodendrocytes

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14
Q

In the PNS, myelination is made from what cells?

A

Schwann cells

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15
Q

What is myelination important for?

A

Sensory & motor transmission (PNS)
Neuron to neuron communication (CNS)

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16
Q

Afferent stimulation =

A

Carry messages to CNS
Alerts about environment

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17
Q

Efferent stimulation =

A

Motor neurons carry messages AWAY FROM CNS
causes muscle movement

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18
Q

What’s the ave. percentage of neuronal cells in the brain?

A

10 - 15%

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19
Q

What is the ave. % of glial cells in the brain?

A

85%

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20
Q

What do glia do?

A

Glue CNS together
Supply nutrients to soma
Insulate neurons
Destroy/remove dead neurons

GLIA = GLUE

21
Q

How many types of neuroglial cells are there?

A

6

22
Q

How many types of glia in the PNS?

A

2

23
Q

How many types of glia in the CNS?

A

4

24
Q

What are the 2 types of glia in the PNS?

A

Schwann Cells
Satellite Cells

25
Q

What are the 4 types of glia cells in the CNS?

A
  1. Astrocytes
  2. Oligodendrocytes
  3. Microglia
  4. Ependymal cell
26
Q

What is the connectome?

A

A comprehensive map of neural connections in the brain
‘Wiring diagram’
INCL. every neuron, synapse & component

27
Q

What is the connectome trying to achieve?

A

Map functional neuronal connectivity and structures

Identify how these complexities influence behaviour and consciousness

28
Q

How many cranial nerves are there?

A

12

29
Q

Name the 12 cranial nerves in order

A

I - Olfactory
II - Optic
III - Oculomotor
IV - Trochlear
V - Trigeminal
VI - Abducens
VII - Facial
VIII - Vestibulocochlear
IX - Glossopharyngeal
X - Vagus
XI - Accessory
XII - Hypoglossal

30
Q

What is the BBB?

A

A semipermeable barrier between the blood and the brain produced by the cells in the walls of the brain’s capillaries.

31
Q

Where is the BBB?

A

Around the brain

32
Q

What does the BBB do?

A

he blood–brain barrier helps prevent pathogens from entering the brain, it can also prevent molecules from entering.

33
Q

How does the BBB function?

A

The BBB regulates the composition of extracellular neuronal fluid

Protects the brain from harmful chemicals

34
Q

Why does the BBB do it’s (function)?

A

To protect the brain

35
Q

How does the reflex in Fig. 2.13 work in foundations of behavioural neuroscience?

A
36
Q

What is an interneuron?

A

A neuron located entirely within the central nervous system.

37
Q

What direction is anterograde?

A

In a direction along an axon from the cell body toward the terminal buttons.

38
Q

What direction is retrograde?

A

In a direction along an axon from the terminal buttons toward the cell body.

39
Q

What is a cytoskeleton?

A

Formed of microtubules and other protein fibers, linked to each other and forming a cohesive mass that gives a cell its shape

40
Q

What is a microtubule?

A

A long strand of bundles protein filaments
hollow core;
part of the cytoskeleton
transports substances within the cell.

41
Q

What does the nucleus contain?

A

Chromosomes

42
Q

What is a chromosome?

A

A strand of DNA, with associated proteins, found in the nucleus; carries genetic information.

43
Q

What does DNA stand for?

A

deoxyribonucleic acid (DNA)

44
Q

What is a gene?

A

The functional unit of the chromo- some, which directs synthesis of one or more proteins.

45
Q

What is an astrocyte?

A

A glial cell that provides sup- port for neurons of the central nervous system, provides nutrients and other substances, and regulates the chemical composition of the extracellular fluid.

ASTROCYTE = STAR CELL

46
Q

What is phagocytosis?

A

The process by which cells engulf and digest other cells or debris caused by cellular degeneration.

47
Q

What is the function of oligodentrocytes?

A

Provide support to axons
Produce myelin sheath

48
Q

What are 6 things microglia cells do?

A

Smallest glial cells
Phagocytosis
Engulfs & breaksdown dead & dying neurons
Brain immunity
Protects brain from invasions
Associated with inflammatory reactions

49
Q

Is the BBB selectively permeable?

A

Yes

50
Q

How is the BBB formed?

A

CNS capillaries don’t have gaps
substances cannot leave the blood to enter the brain. The tightly packed cells of the capillaries in the brain make up the blood–brain barrier.

51
Q

What area of the brain controls vomiting and why?

A

postrema
The blood–brain barrier is much weaker there
neurons detect the
presence of toxic substances