NEU531 - Spinal control of movement Flashcards

1
Q
A
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2
Q

Describe lower motor neurons and their segmental
organisation.

A
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3
Q

Describe alpha motor neurons and the inputs to alpha
motor neurons.

A
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4
Q

Explain the mechanisms that mediate the graded
control of muscle contraction by alpha motor neurons.

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5
Q

Explain the different types of motor units.

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6
Q

Describe the spinal control of motor units.

A
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7
Q

Explain the
process of proprioception, and the role of the muscle
spindles in this process.

A
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8
Q

Describe the concept of myotatic reflexes.

A
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9
Q

Explain the
myotatic reflex mechanism.

A
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10
Q

Explain the process of generation of spinal motor
programs for walking.

A
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11
Q

Are lower motor neurons innervating the ventral or dorsal spinal cord areas?

A

Ventral horn of spinal cord

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12
Q

What are axial muscles associated with?

A

Trunk movements

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13
Q

What are proximal muscles associated with?

A
  • Shoulders
  • Knees
  • Elbows
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14
Q

What are distal muscles associated with?

A
  • Hands, feet, fingers, toes
    DISTAL = DIGITS
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15
Q

What is a Motor neuron pool:

A

All the motor neurons that innervate a single muscle

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16
Q

What is a motor unit?

A

Motor neuron
and all the muscle fibres it
innervates

17
Q

What are the 3 main ALPHA MOTOR NEURON inputs?

A
  • Muscle spindle sensory input
  • Spinal interneurons
  • BRAIN: Upper motor neurons
18
Q

WHAT is the LARGEST input to the ALPHA MOTOR NEURONS?

A

Interneuron input
E & I neurons

19
Q

What are red muscle fibres associated with?

A
  • Aerobic
  • Mitochondria
  • Slow contraction
  • Sustain contractions
  • Non-fatigueable
20
Q

What are WHITE muscle fibers associated with?

A
  • Fewer mitochondria
  • anaerobic
  • contract and fatigue rapidly
  • FAST
21
Q

What are the 2 types of white muscle fibres?

A
  1. Fatigue-resistant fast fibers
  2. fast fatigueable fibres
22
Q

What are SLOW motor units associated with?

A
  • Slowly fatiguing red fibres
23
Q

Are red muscle fibres fast or slow?

24
Q

What neurotransmitter is usually associated with muscle excitation?

A

Aceytlcholine

25
What does NMJ stand for?
Neuro muscular junction
26
What receptors do ACh bind to?
Nicotinic acetylcholine receptor
27
What is ACh inactivated by?
cholinesterase
28
What id the crossed innervation experiment?
John Eccles
29
30
LEARN THE MUSCLE PHYSIOLOGYYYYYY
31
LEARN SLIDING-FILAMENT MODEL
32
What is the myotatic reflex?
Stretch reflex: Muscle pulled→ tendency to pull back – Feedback loop 'KNEE REFLEX;
33
34
35
Most input to alpha motor neurons mediated by WHAT?
spinal interneurons
36
What is the Crossed-Extensor reflex?
Activation of extensor muscles and inhibition of flexors on opposite side
37
Circuit for rhthmic alternating activity