NEUR532 - The Cerebellum Flashcards
Who came up with the name cerebellum?
Galen
What are the 3 lobes of the cerebellar cortex?
Molecular layer
- Purkinje Layer
- Granule cells
What are the 3 cerebellar cortical layers and cell types found in each region?
Describe the major efferent and afferent circuitry of the cerebellar cortex including the local circuitry
Define the 3 major functional subdivisions of the cerebellum including their anatomical location, afferent/efferent pathways and functions
What are the key associative functions of the cerebellum?
- Motor area of the brain
- Maintains muscle contractions
- Muscle memory and learning
Pathways
- LMN: lower motor neurons
- BS: brainstem
- SC: spinal cord
What are the 2 major anatomical divisions of the cerebellum?
- Cerebellar cortex
- Deep cerebellar nuclei
What are the 3 layers of the cerebellar cortex?
- Pontocerebellum
- Spinocerebellum
- Vestibulocerebellum
What are the 3 nuclei within the deep cerebellar nuclei?
- Dentate nucleus
- Interposed nuclei
- Fastigial nucleus
What are the 3 lobes within the cerebellum?
- Flocculonodular
- Anterior
- Posterior
What does the vermis mean?
“The worm”
What is the folucculus lobe associated with?
Balance & Equilibrium
What does folia mean?
- Highly folded surface
What are the 3 cortical layers of the cerebellar cortex?
- Molecular
- Purkinje cells
- Granule cells
What do the purkinje cells do within the cerebellum?
- They are the major output neurons of the cerebellar cortex
What do climbing fibres synapse onto?
A single Purkinje cell
What do the mossy fibres synapse onto?
- Excitatory interneurons (granule cells)
then form parallel fibers
What do the mossy fibres synapse onto?
- Excitatory interneurons (granule cells)
then form parallel fibers
Purkinje cells
Cerebellar cortex structure