Pathological Fractures

Question 1

What type of integrity occurs secondary to an underlying disease process?

Answer 1

Integrity that occurs secondary to an underlying disease process, rather than due to trauma.

Question 2

List three types of malignant neoplasms related to bone integrity.

Answer 2

• Primary bone tumours
• Metastatic cancer
• Multiple myeloma

Question 3

Name three primary bone tumors.

Answer 3

• Osteosarcoma
• Ewing’s sarcoma
• Chondrosarcoma

Question 4

What are benign bone lesions that can affect integrity?

Answer 4

• Osteoporotic vertebral compression fractures
• Osteomalacia/rickets
• Paget’s disease of bone (osteitis deformans)

Question 5

Identify two non-neoplastic conditions that can affect bone integrity.

Answer 5

• Rheumatoid arthritis
• Osteogenesis imperfecta

Question 6

What are iatrogenic factors that can impact bone integrity?

Answer 6

• Corticosteroid use
• Radiation therapy

Question 7

Which infectious disease can lead to compromised bone integrity?

Answer 7

• Tuberculosis (vertebral involvement → Pott’s disease)
• Osteomyelitis

Question 8

Name two endocrine disorders that can affect bone integrity.

Answer 8

• Hyperparathyroidism
• Hypogonadism