Human Papilloma Virus

Question 1

What type of virus is HPV?

Answer 1

Double-stranded DNA virus

Question 2

What are the two classes of proliferative lesions caused by HPV?

Answer 2

• High-risk (malignant neoplasms)
• Low-risk (benign lesions)

Question 3

Name two high-risk HPV types associated with cervical cancer.

Answer 3

• HPV-16
• HPV-18

Question 4

Name two low-risk HPV types associated with genital warts.

Answer 4

• HPV-6
• HPV-11

Question 5

What are the main transmission methods for HPV?

Answer 5

• Direct skin-skin contact during sexual intercourse
• Contact with contaminated surfaces/objects
• Perinatal vertical transmission

Question 6

List four risk factors for HPV infection.

Answer 6

• Early age first sexual intercourse
• High number of sexual partners
• Condomless sexual intercourse
• Immunosuppressed (including HIV)

Question 7

What percentage of HPV cases are asymptomatic?

Answer 7

70-90%

Question 8

Within how many months do most HPV cases clear?

Answer 8

12-14 months

Question 9

What are the characteristics of genital warts?

Answer 9

• Single or multiple 2-5mm cauliflower-like growths
• Associated with itch, irritation, pain, and bleeding

Question 10

How are genital warts diagnosed?

Answer 10

On examination

Question 11

What is the management focus for HPV infection?

Answer 11

Treatments aimed at destroying or removing warts/lesions

Question 12

What patient advice is recommended for HPV management?

Answer 12

• Smoking cessation
• Barrier contraception

Question 13

What is the name of the 9-valent HPV vaccine?

Answer 13

Gardasil 9

Question 14

Which HPV types are covered by the Gardasil 9 vaccine?

Answer 14

• HPV 6
• HPV 11
• HPV 16
• HPV 18
• HPV 31
• HPV 33
• HPV 45
• HPV 52
• HPV 58